Evidence map›Paper›PMID 30004427›Full record

ArticleMolecules (Basel, Switzerland)2018

A3, a Scorpion Venom Derived Peptide Analogue with Potent Antimicrobial and Potential Antibiofilm Activity against Clinical Isolates of Multi-Drug Resistant Gram Positive Bacteria.

Ammar Almaaytah, Ahmad Farajallah, Ahmad Abualhaijaa, Qosay Al-Balas

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ammar AlmaaytahDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 2110, Jordan. amalmaaytah@just.edu.jo.ORCID 0000-0002-7804-3313
Ahmad FarajallahDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 2110, Jordan. ahmad1990_frj@yahoo.com.
Ahmad AbualhaijaaDepartment of Applied Biological Sciences, Faculty of Science and Arts, Jordan University of Science and Technology, Irbid 2110, Jordan. ahkhaled18@yahoo.com.
Qosay Al-BalasDepartment of Medicinal Chemistry, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 2110, Jordan. qabalas@just.edu.jo.ORCID 0000-0002-8350-900X
Jordan University of Science and Technology · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current research in the field of antimicrobials is focused on developing novel antimicrobial agents to counteract the huge dilemma that the human population is mainly facing in regards to the rise of bacterial resistance and biofilm infections. Host defense peptides (HDPs) are a promising group of molecules for antimicrobial development as they display several attractive features suitable for antimicrobial activity, including their broad spectrum of activity and potency against bacteria. AamAP1 is a novel HDP that belongs to the venom of the North African scorpion

Indexed as

AnimalsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesBiofilmsCell LineChlorocebus aethiopsDrug Resistance, Multiple, BacterialGram-Negative BacteriaGram-Positive BacteriaHEK293 CellsHumansMicrobial Sensitivity TestsScorpion VenomsVero CellsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesScorpion Venomsantibiofilm activityantimicrobial activitybacterial resistancehost defense peptidesscorpion venomssynergism

Identifiers

PMID30004427
PMCPMC6100099
OpenAlexW2803263806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.