Evidence map›Paper›PMID 30004385›Full record

ArticleeLife2018

Lipoate-binding proteins and specific lipoate-protein ligases in microbial sulfur oxidation reveal an atpyical role for an old cofactor.

Xinyun Cao, Tobias Koch, Lydia Steffens, Julia Finkensieper, Renate Zigann, John E Cronan, Christiane Dahl

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Diversity and ecology of microbial sulfur metabolism.Nature reviews. Microbiology · 2025
    Review
  6. Article
  7. Article
  8. Lipoic acid attachment to proteins: stimulating new developments.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. In the AlphaproteobacteriumAntioxidants (Basel, Switzerland) · 2023
    Article
  13. Article
  14. ONature communications · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Xinyun Cao *Department of Biochemistry, University of Illinois, Urbana, United States.ORCID http://orcid.org/0000-0002-7346-3909
Tobias Koch *Institut für Mikrobiologie and Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0003-3390-3428
Lydia SteffensInstitut für Mikrobiologie and Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany.
Julia FinkensieperInstitut für Mikrobiologie and Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany.
Renate ZigannInstitut für Mikrobiologie and Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany.
John E CronanDepartment of Biochemistry, University of Illinois, Urbana, United States.ORCID http://orcid.org/0000-0002-7064-312X
Christiane DahlInstitut für Mikrobiologie and Biotechnologie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0001-8288-7546
University of Bonn · DEUniversity of Illinois Urbana-Champaign · US

Funding

GENETIC APPROACHES TO REGULATION OF LIPID METABOLISMR01AI015650 · NIAID · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI CRONAN, JOHN E. · 1985 to 2022
$12.0M
GENETIC APPROACHES TO REGULATION OF LIPID METABOLISMR37AI015650 · NIAID · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI CRONAN, JOHN E. · 1994 to 2003
$1.8M
NIAID NIH HHS R01 AI015650NIAID NIH HHS R37 AI015650NIH HHS AI15650
6 · The paper itself

Abstract

Many Bacteria and Archaea employ the heterodisulfide reductase (Hdr)-like sulfur oxidation pathway. The relevant genes are inevitably associated with genes encoding lipoate-binding proteins (LbpA). Here, deletion of the gene identified LbpA as an essential component of the Hdr-like sulfur-oxidizing system in the Alphaproteobacterium

Indexed as

Bacillus subtilisEscherichia coliHyphomicrobiumLigasesOxidation-ReductionOxidoreductasesSulfurThioctic Acidheterodisulfide reductaseLigasesOxidoreductasesSulfurThioctic AcidbiochemistryB. subtilischemical biologydissimilatory sulfur oxidationE. coliheterodisulfide reductaseHyphomicrobium denitrificansinfectious diseaselipoate binding proteinslipoate-binding proteinsmicrobiologysulfur-oxidizing bacteriaThioalkalivibrio sp. K90mixThiorhodospira sibirica

Identifiers

PMID30004385
PMCPMC6067878
OpenAlexW2884239882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.