Evidence map›Paper›PMID 30004040›Full record

ArticleAsian journal of andrology

Nanotechnology-assisted adipose-derived stem cell (ADSC) therapy for erectile dysfunction of cavernous nerve injury:

Han Wu, Wen-Hao Tang, Lian-Ming Zhao, De-Feng Liu, Yu-Zhuo Yang, Hai-Tao Zhang, Zhe Zhang, Kai Hong, Hao-Cheng Lin, Hui Jiang

Open access · goldAbstract read
In one paragraph

Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Research Advances in Stem Cell Therapy for Erectile Dysfunction.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024
    Review
  7. Nanotechnology in sexual medicine.The journal of sexual medicine · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Adipose-derived stem cells modified byNeural regeneration research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Han WuDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.
Wen-Hao TangDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.
Lian-Ming ZhaoDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.
De-Feng LiuDepartment of Reproductive Medicine Center, Peking University Third Hospital, Beijing 100191, China.
Yu-Zhuo YangDepartment of Reproductive Medicine Center, Peking University Third Hospital, Beijing 100191, China.
Hai-Tao ZhangDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.
Zhe ZhangDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.
Kai HongDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.
Hao-Cheng LinDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.
Hui JiangDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.
Peking University Third Hospital · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cell therapy is a potentially promising option for erectile dysfunction; however, its risk of tumorigenicity is a clinical hurdle and the risk is positively related to the number of injected cells. Our previous study showed that nanotechnology improved adipose-derived stem cell (ADSC) therapy for erectile dysfunction of cavernous nerve injury (CNI) by attracting cells in the corpus cavernosum. These results indicated the possibility of using a reduced dosage of ADSCs for intracavernous injection. In this exploratory study, we used lower dosage (2 × 10

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationAnimalsCell TrackingDisease Models, AnimalErectile DysfunctionMalePenisPeripheral Nerve InjuriesRatsRats, Sprague-DawleyTreatment Outcomeadipose-derived stem cell (ADSC)cavernous nerve injurycell trackingerectile dysfunction

Identifiers

PMID30004040
PMCPMC6116694
OpenAlexW2867037497

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.