ReviewInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2018
A meta-analysis of effectiveness of interventions to improve adherence in pregnant women receiving antiretroviral therapy in sub-Saharan Africa.
Review in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Adherence to option B + antiretroviral therapy and associated factors in pregnant and breastfeeding women in Sub-Saharan Africa: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Interventions to improve antiretroviral adherence in HIV-infected pregnant women: A systematic review and meta-analysis.Frontiers in public health · 2022Pooled it
- Trial
- The effects of revised peer-counselor support on the PMTCT cascade of care: results from a cluster-randomized trial in Kenya (the EMMA study).BMC infectious diseases · 2023Trial
- Real-time Feedback to Improve HIV Treatment Adherence in Pregnant and Postpartum Women in Uganda: A Randomized Controlled Trial.AIDS and behavior · 2022Trial
- Article
- Incidence of loss to follow-up and associated factors among mothers on antiretroviral therapy in the context of elimination of mother-to-child transmission of HIV in two health districts of Bobo-Dioulasso in Burkina Faso.BMC women's health · 2025Article
- Attitudes toward digital pill systems for antiretroviral therapy adherence among pregnant and postpartum women living with HIV in South Africa: a qualitative study.Frontiers in psychiatry · 2025Article
- Gender transformative approaches in mHealth for maternal healthcare in sub-Saharan Africa: a systematic review.Frontiers in digital health · 2023Review
- Protocol for the pilot quasi-experimental controlled trial of a gender-responsive implementation strategy with providers to improve HIV outcomes in Uganda.Pilot and feasibility studies · 2022Article
- Article
- A Review of Interventions to Enhance HIV Medication Adherence.Current HIV/AIDS reports · 2021Review
- Role of temporal discounting in a conditional cash transfer (CCT) intervention to improve engagement in the prevention of mother-to-child transmission (PMTCT) cascade.BMC public health · 2021Article
- Article
- Cultivating a universal understanding of ART adherence: Comments on "A meta-analysis of effectiveness of interventions to improve adherence in pregnant women receiving antiretroviral therapy in sub-Saharan Africa".International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020Article
- Article
- A Case Study of an Effective and Sustainable Antiretroviral Therapy Program in Rural South Africa.AIDS patient care and STDs · 2019Article
- A tool for estimating antiretroviral medication coverage for HIV-infected women during pregnancy (PMTCT-ACT).Global health research and policy · 2019Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe evaluated the effectiveness of interventions aimed at improving antiretroviral therapy (ART) adherence during pregnancy in sub-Saharan Africa.
methodsFor this meta-analysis, the following databases were searched: MEDLINE Complete, Embase, Global Health, CINAHL Complete, and Google Scholar. Randomized and nonrandomized studies were considered for inclusion if they involved an intervention with the intent of improving medication adherence among pregnant women taking ART in sub-Saharan Africa. Databases were searched from inception to the end of August 2017. The primary outcome assessed was adherence to ART, defined as the proportion of women adherent to treatment in the control and intervention groups. Risk ratios and random effect meta-analysis were undertaken, and heterogeneity was examined with the I
resultsThe systematic search of databases yielded a total of 402 articles, of which 19 studies were selected for meta-analysis with a total of 27,974 participants. Nine types of interventions were identified in the 19 studies to improve ART adherence. The test for the subgroup differences showed that there was a statistically significant difference among the 9 subgroups of interventions, χ
conclusionThe use of device reminder, a combination of social support and structural support, and education, social support and structural support has the potential to improve ART adherence during pregnancy. Good quality prospective observational studies and randomized control trials are needed in sub-Saharan Africa to determine the most effective interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.