Evidence map›Paper›PMID 30003464›Full record

ArticleWorld journal of microbiology & biotechnology2018

Molecular characterization of bmyC gene of the mosquito pupicidal bacteria, Bacillus amyloliquefaciens (VCRC B483) and in silico analysis of bacillomycin D synthetase C protein.

Mathivanan Ashokkumar, Geetha Irudayaraj, Nandakumar Yellapu, Arulsamy Mary Manonmani

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Article in World journal of microbiology & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mathivanan AshokkumarUnit of Microbiology and Molecular Biology, Vector Control Research Centre, Indian Council of Medical Research (ICMR), Puducherry, 605 006, India.
Geetha IrudayarajUnit of Microbiology and Molecular Biology, Vector Control Research Centre, Indian Council of Medical Research (ICMR), Puducherry, 605 006, India.
Nandakumar YellapuBiomedical Informatics Centre, Vector Control Research Centre, Indian Council of Medical Research (ICMR), Puducherry, 605 006, India.
Arulsamy Mary ManonmaniUnit of Microbiology and Molecular Biology, Vector Control Research Centre, Indian Council of Medical Research (ICMR), Puducherry, 605 006, India. ammanonmani@yahoo.com.
Indian Council of Medical Research · INVector Control Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A strain of Bacillus amyloliquefaciens (VCRC B483) exhibiting mosquito pupicidal, keratinase and antimicrobial activities was isolated from mangrove forest ecosystem of Andaman and Nicobar Islands. Molecular characterization of the strain showed the presence of lipopeptide encoding bmyC gene. Phylogenetic tree based on protein sequence of this gene exhibited homology with mycosubtilin synthetase of Bacilus atropheus and Iturin synthetase of Bacillus subtilis and B. amyloliquefaciens. This is the first report on the evolutionary conservation of amino acids concerned with the function and structure of bmyC protein of B. amyloliquefaciens. The presence of valine at the 1197th position in our strain was found to be unique and different from the existing strains of B. subtilis and B. amyloliquefaciens. Molecular modelling studies revealed significant changes in the structure of epimerization domain of the bmyC protein with A1197V variation. Crude metabolite of this strain exhibited antifungal activity against Fusarium sp. and Carvularia sp.

Indexed as

Amino Acid SequenceAnimalsAntifungal AgentsAntimicrobial Cationic PeptidesBacillusBacillus amyloliquefaciensBacterial ProteinsCulicidaeFusariumGenes, BacterialLipopeptidesModels, MolecularMultienzyme ComplexesPeptidesPhylogenySequence AlignmentAntifungal AgentsAntimicrobial Cationic Peptidesbacillomycin DBacterial ProteinsLipopeptidesMultienzyme Complexesmycosubtilin synthetasePeptidesBacillomycinBacillus amyloliquefaciensLipopeptide

Identifiers

PMID30003464
OpenAlexW2874936966

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.