ArticleSocial psychiatry and psychiatric epidemiology2019
Time course of panic disorder and posttraumatic stress disorder onsets.
Article in Social psychiatry and psychiatric epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- Impact of posttraumatic stress disorder and comorbid psychiatric conditions on suicide reattempts.European journal of psychotraumatology · 2025Trial
- Posttraumatic stress disorder in individuals seeking treatment for opioid use disorder in Vermont.Preventive medicine · 2021Trial
- DNA methylation as a new frontier in treating fear-related disorders: A need for careful evaluation.World journal of psychiatry · 2025Article
- Prevalence and Health Care Utilization of Posttraumatic Stress Disorder and Other Trauma-Related Mental Health Diagnoses in a Large, Integrated Health Care System.The Permanente journal · 2025Article
- The psychological impact of conflict in the Middle East from 2023 to 2025 on Australian communities: a prospective cohort study.The Lancet regional health. Western Pacific · 2025Article
- Early life stress and hormonal status influence orexin-1 receptor expression in structures regulating cardiorespiratory responses to COExperimental physiology · 2025Article
- Capnometry-Guided Respiratory Intervention in Veteran PTSD: Impact on Symptom Clusters.Healthcare (Basel, Switzerland) · 2025Article
- Psychological Impact on Firefighters After the 2022 Amok Attack in Berlin at Tauentzienstraße.Healthcare (Basel, Switzerland) · 2025Article
- Steady electrocorticogram characteristics predict specific stress-induced behavioral phenotypes.Frontiers in neuroscience · 2023Article
- Real-world outcomes of an innovative digital therapeutic for treatment of panic disorder and PTSD: A 1,500 patient effectiveness study.Frontiers in digital health · 2022Article
- Investigation of a Capnometry Guided Respiratory Intervention in the Treatment of Posttraumatic Stress Disorder.Applied psychophysiology and biofeedback · 2021Article
- Mental Health Literacy: a Critical Target for Narrowing Racial Disparities in Behavioral Health.International journal of mental health and addiction · 2021Article
- Prevalence, New Incidence, Course, and Risk Factors of PTSD, Depression, Anxiety, and Panic Disorder during the Covid-19 Pandemic in 11 Countries.Healthcare (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
purposePosttraumatic stress disorder (PTSD) often co-occurs with panic disorder (PD), with some etiological models positing a causal role of panic reactivity in PTSD onset; however, data addressing the temporal ordering of these conditions are lacking. The aim of this study was to examine the bi-directional associations between PD and PTSD in a nationally representative, epidemiologic sample of trauma-exposed adults.
methodsParticipants were community-dwelling adults (62.6% women; M
resultsPD was significantly associated with subsequent onset of PTSD (HR 1.210, 95%CI = 1.207-1.214, p < .001), and PTSD was significantly associated with onset of PD (HR 1.601, 95% CI 1.597-1.604, p < .001). The association between PTSD and subsequent PD was stronger in magnitude than that between PD and subsequent PTSD (Z = - 275.21, p < .01). Men evidenced stronger associations between PD and PTSD compared to women.
conclusionsResults were consistent with a bidirectional pathway of risk, whereby PD significantly increased risk for the development of PTSD, and PTSD significantly increased risk for PD. Given the association between PTSD and subsequent PD, particularly among men, clinicians may consider supplementing PTSD treatment with panic-specific interventions, such as interoceptive exposure, to prevent or treat this disabling comorbidity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.