Evidence map›Paper›PMID 30003145›Full record

ArticleSynthetic biology (Oxford, England)2018

Simultaneous monitoring of transcription and translation in mammalian cell-free expression in bulk and in cell-sized droplets.

Shue Wang, Sagardip Majumder, Nicholas J Emery, Allen P Liu

Abstract read
In one paragraph

Article in Synthetic biology (Oxford, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. T7Max transcription system.Journal of biological engineering · 2023
    Article
  6. Review
  7. Real-time monitoring strategies for optimization ofFrontiers in molecular biosciences · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shue WangDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.
Sagardip MajumderDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.
Nicholas J EmeryDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.
Allen P LiuDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-0309-7018

Funding

Building artificial plateletsDP2HL117748 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, ALLEN PO-CHIH · 2012 to 2012
$2.3M
NHLBI NIH HHS DP2 HL117748
6 · The paper itself

Abstract

Transcription and translation are two critical processes during eukaryotic gene expression that regulate cellular activities. The development of mammalian cell-free expression (CFE) systems provides a platform for studying these two critical processes

Indexed as

in vitro transcription and translationmammalian cell-free expressionsingle-emulsion droplets

Identifiers

PMID30003145
PMCPMC6034425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.