ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2018
Underdiagnosis of mild cognitive impairment: A consequence of ignoring practice effects.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07420426 (Instant Message-delivered Personalised Acceptance and Commitment Therapy), which is not on this map. Cited by 52 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Instant Message-delivered Personalised Acceptance and Commitment Therapy (IMPACT) for Neuropsychiatric Symptoms in Persons With Mild Cognitive Impairment: a Mixed Methods Study
Who cites it
52 citing papers in PubMed.
- A pragmatic trial of a group intervention in senior housing communities to increase resilience.International psychogeriatrics · 2020Trial
- Mediators of attachment, frailty, and mild cognitive impairment in older adults.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- A continuous-time approach to short-term activity-cognition dynamics.Psychology and aging · 2026Article
- Young adult urbanicity, late midlife neighborhood disadvantage, and cognitive functioning in community-dwelling older men.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Cognitive Assessment for Neuropsychological Impairments in Dogs (CANID): An Efficient, Repeatable, and Sensitive Evaluation for Age-related Cognitive Dysfunction.Research square · 2026Article
- Subjective memory concern, negative affect, and cortical microstructural integrity in community-dwelling middle-aged men.GeroScience · 2026Article
- Comparisons between two adapted versions of the Rey Auditory Verbal Learning Test in Brazilian adults: Effects of age and education.Journal of neuropsychology · 2026Article
- Practice effects persist over two decades of cognitive testing: Implications for longitudinal research.medRxiv : the preprint server for health sciences · 2025Article
- History of chronic pain and opioid use is associated with cognitive decline and mild cognitive impairment.Journal of the International Neuropsychological Society : JINS · 2025Article
- [Brain check-up: a structured approach diagnosing mild cognitive impairment in the primary care setting].Zeitschrift fur Gerontologie und Geriatrie · 2024Article
- Developing a prediction model for cognitive impairment in older adults following critical illness.BMC geriatrics · 2024Article
- Brain reserve in midlife is associated with executive function changes across 12 years.Neurobiology of aging · 2024Article
- Review
- Associations of plasma neurofilament light chain with cognition and neuroimaging measures in community-dwelling early old age men.Alzheimer's research & therapy · 2024Article
- Executive functioning trajectories and their prospective association with inflammatory biomarkers in schizophrenia and non-psychiatric comparison participants.Progress in neuro-psychopharmacology & biological psychiatry · 2024Article
- FORTCARE-MCI study protocol: evaluation of Fortasyn Connect in the management of mild cognitive impairment in primary care.Frontiers in neurology · 2024Article
- Association Between Traumatic Brain Injury and Cognitive Decline Among Middle-to-Older Aged Men in the Vietnam Era Twin Study of Aging.Neurotrauma reports · 2024Article
- Concordance Between Logical Memory and Craft Story 21 in Community-Dwelling Older Adults: The Role of Demographic Factors And Cognitive Status.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2023Article
- Urinary Glyphosate, 2,4-D and DEET Biomarkers in Relation to Neurobehavioral Performance in Ecuadorian Adolescents in the ESPINA Cohort.Environmental health perspectives · 2023Article
- Higher cortical thickness/volume in Alzheimer's-related regions: protective factor or risk factor?Neurobiology of aging · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
introductionLongitudinal testing is necessary to accurately measure cognitive change. However, repeated testing is susceptible to practice effects, which may obscure true cognitive decline and delay detection of mild cognitive impairment (MCI).
methodsWe retested 995 late-middle-aged men in a ∼6-year follow-up of the Vietnam Era Twin Study of Aging. In addition, 170 age-matched replacements were tested for the first time at study wave 2. Group differences were used to calculate practice effects after controlling for attrition effects. MCI diagnoses were generated from practice-adjusted scores.
resultsThere were significant practice effects on most cognitive domains. Conversion to MCI doubled after correcting for practice effects, from 4.5% to 9%. Importantly, practice effects were present although there were declines in uncorrected scores. DISCUSSION: Accounting for practice effects is critical to early detection of MCI. Declines, when lower than expected, can still indicate practice effects. Replacement participants are needed for accurately assessing disease progression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.