Evidence map›Paper›PMID 30003101›Full record

ArticleBioMed research international2018

Synergistic Effect of Endogenous and Exogenous Aldehydes on Doxorubicin Toxicity in Yeast.

Jana S Miles, Samantha J Sojourner, Aurellia M Whitmore, Devon Freeny, Selina Darling-Reed, Hernan Flores-Rozas

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jana S MilesCollege of Pharmacy and Pharmaceutical Sciences, Florida A&M University, 1415 S. Martin Luther King, Jr. Blvd. NPB Phase-2-L147, Tallahassee, FL 32307, USA.
Samantha J SojournerCollege of Pharmacy and Pharmaceutical Sciences, Florida A&M University, 1415 S. Martin Luther King, Jr. Blvd. NPB Phase-2-L147, Tallahassee, FL 32307, USA.
Aurellia M WhitmoreCollege of Pharmacy and Pharmaceutical Sciences, Florida A&M University, 1415 S. Martin Luther King, Jr. Blvd. NPB Phase-2-L147, Tallahassee, FL 32307, USA.
Devon FreenyCollege of Pharmacy and Pharmaceutical Sciences, Florida A&M University, 1415 S. Martin Luther King, Jr. Blvd. NPB Phase-2-L147, Tallahassee, FL 32307, USA.
Selina Darling-ReedCollege of Pharmacy and Pharmaceutical Sciences, Florida A&M University, 1415 S. Martin Luther King, Jr. Blvd. NPB Phase-2-L147, Tallahassee, FL 32307, USA.
Hernan Flores-RozasCollege of Pharmacy and Pharmaceutical Sciences, Florida A&M University, 1415 S. Martin Luther King, Jr. Blvd. NPB Phase-2-L147, Tallahassee, FL 32307, USA.ORCID 0000-0003-1876-7173
Florida Agricultural and Mechanical University · US

Funding

Recruitment and HiringG12MD007582 · NIMHD · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI SOLIMAN, KARAM F.A. · 2012 to 2017
$16.0M
Targeted Nanocarrier Combination Based Therapy for Lung CancerP20MD006738 · NIMHD · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI RAHMAN, SALEH MD. MAHMUDUR · 2012 to 2016
$5.6M
NIMHD NIH HHS G12 MD007582NIMHD NIH HHS P20 MD006738
6 · The paper itself

Abstract

Anthracyclines are frequently used to treat many cancers including triple negative breast cancer, which is commonly observed in African-American women (AA), and tend to be more aggressive, carry worse prognoses, and are harder to manage because they lack molecular targets. Although effective, anthracyclines use can be limited by serious side effects and eventually the development of drug resistance. In

Indexed as

Saccharomyces cerevisiaeAldehydesAntibiotics, AntineoplasticDoxorubicinFemaleHumansSaccharomyces cerevisiae ProteinsAldehydesAntibiotics, AntineoplasticDoxorubicinSaccharomyces cerevisiae Proteins

Identifiers

PMID30003101
PMCPMC5998155
OpenAlexW2807375753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.