Evidence map›Paper›PMID 30003037›Full record

ArticleNeuroImage. Clinical2018

Altered cortical functional network in major depressive disorder: A resting-state electroencephalogram study.

Miseon Shim, Chang-Hwan Im, Yong-Wook Kim, Seung-Hwan Lee

Open access · goldAbstract read
In one paragraph

Article in NeuroImage. Clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Magnetoencephalography changes in cervical spondylotic myelopathy: a study of resting-state and somatosensory evoked magnetic fields.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  20. Brain Functional Network and Amino Acid Metabolism Association in Females with Subclinical Depression.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Miseon ShimPsychiatry Department, University of Missouri, Kansas City, USA; Clinical Emotion and Cognition Research Laboratory, Goyang, Republic of Korea.
Chang-Hwan ImDepartment of Biomedical Engineering, Hanyang University, Seoul, Republic of Korea.
Yong-Wook KimDepartment of Biomedical Engineering, Hanyang University, Seoul, Republic of Korea; Clinical Emotion and Cognition Research Laboratory, Goyang, Republic of Korea.
Seung-Hwan LeeClinical Emotion and Cognition Research Laboratory, Goyang, Republic of Korea; Psychiatry Department, Ilsan Paik Hospital, Inje University, Goyang, Republic of Korea. Electronic address: lshpss@paik.ac.kr.
Hanyang University · KRInje University Ilsan Paik Hospital · KRKorea Aerospace University · KRUniversity of Missouri–Kansas City · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Electroencephalogram (EEG)-based brain network analysis is a useful biological correlate reflecting brain function. Sensor-level network analysis might be contaminated by volume conduction and does not explain regional brain characteristics. Source-level network analysis could be a useful alternative. We analyzed EEG-based source-level network in major depressive disorder (MDD). Method: Resting-state EEG was recorded in 87 MDD and 58 healthy controls, and cortical source signals were estimated. Network measures were calculated: global indices (strength, clustering coefficient (CC), path length (PL), and efficiency) and nodal indices (eigenvector centrality and nodal CC) in six frequency. Correlation analyses were performed between network indices and symptom scales. Results: At the global level, MDD showed decreased strength, CC in theta and alpha bands, and efficiency in alpha band, while enhanced PL in alpha band. At nodal level, eigenvector centrality of alpha band showed region dependent changes in MDD. Nodal CCs of alpha band were reduced in MDD and were negatively correlated with depression and anxiety scales. Conclusion: Disturbances in EEG-based brain network indices might reflect altered emotional processing in MDD. These source-level network indices might provide useful biomarkers to understand regional brain pathology in MDD.

Indexed as

AdultBrain MappingCerebral CortexElectroencephalographyFemaleHumansMajor Depressive DisorderMaleMiddle AgedNerve NetBrain electrical activity mappingElectroencephalogramMajor depressive disorderSource-level brain network

Identifiers

PMID30003037
PMCPMC6039896
OpenAlexW2808322963

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.