ArticleTranslational vision science & technology2018
Optical Detection of Macular Pigment Formation in Premature Infants.
Article in Translational vision science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Associations Between Carotenoid Status, Visual Outcomes and Cognitive Metrics in Children: A Scoping Review.Nutrients · 2026Article
- Is the Planeterranean Diet the Key Driver Towards Health and Environment Promotion? A Narrative Review.Foods (Basel, Switzerland) · 2025Review
- Perception of #TheDress in childhood is influenced by age and green-leaf preference.Journal of vision · 2024Observational
- Article
- A Role for Data Science in Precision Nutrition and Early Brain Development.Frontiers in psychiatry · 2022Review
- Assessment of Maternal Macular Pigment Optical Density (MPOD) as a Potential Marker for Dietary Carotenoid Intake during Lactation in Humans.Nutrients · 2021Observational
- Review
- Correction for the Influence of Cataract on Macular Pigment Measurement by Autofluorescence Technique Using Deep Learning.Translational vision science & technology · 2021Article
- Maternal Lutein and Zeaxanthin Concentrations in Relation to Offspring Visual Acuity at 3 Years of Age: The GUSTO Study.Nutrients · 2020Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
purposeTo demonstrate the presence of macular pigment in the retina of premature infants, and to examine its changes with age.
methodsThe participants included 40 premature infants. Infants who had received laser photocoagulation for retinopathy of prematurity were excluded. Macular pigment optical density (MPOD) was measured by fundus reflectometry using RetCam3, a digital fundus camera. The reflection imaging was performed for ROP screening. The imaging time points were from a post menstrual age (PMA) of 29 weeks 0 days to 46 weeks 5 days.
resultsThe MPOD levels could be obtained from 39 premature infants. The levels at the first measurement ranged from 0 to 0.18 (mean 0.076, SD 0.044). The earliest time, when a nonvanishing MPOD level was obtained, was at a PMA of 33 weeks and 2 days, and that level was 0.05. The initial examination MPOD levels showed a moderate correlation with age (
conclusionsThe MPOD levels of premature infants were for the first time measured in living eyes. Macular pigment increased linearly with age. TRANSLATIONAL RELEVANCE: Macular pigment increased with the development of macular morphology. This result suggested the importance of nutritional management of infants and mothers during perinatal period.
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Registered trials
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