Evidence map›Paper›PMID 30002819›Full record

ArticleF1000Research2018

iSEE: Interactive SummarizedExperiment Explorer.

Kevin Rue-Albrecht, Federico Marini, Charlotte Soneson, Aaron T L Lun

Abstract read
In one paragraph

Article in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed.

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  15. bioRxiv : the preprint server for biology · 2025
    Article
  16. Transcriptomic Analysis of the Human Habenula in Schizophrenia.The American journal of psychiatry · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kevin Rue-Albrecht *Kennedy Institute of Rheumatology, University of Oxford, Oxford , OX3 7FY, UK.ORCID https://orcid.org/0000-0003-3899-3872
Federico Marini *Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.ORCID https://orcid.org/0000-0003-3252-7758
Charlotte Soneson *SIB Swiss Institute of Bioinformatics, University of Zurich, Zurich, 8057, Switzerland.
Aaron T L Lun *Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 0RE, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data exploration is critical to the comprehension of large biological data sets generated by high-throughput assays such as sequencing. However, most existing tools for interactive visualisation are limited to specific assays or analyses. Here, we present the iSEE (Interactive SummarizedExperiment Explorer) software package, which provides a general visual interface for exploring data in a SummarizedExperiment object. iSEE is directly compatible with many existing R/Bioconductor packages for analysing high-throughput biological data, and provides useful features such as simultaneous examination of (meta)data and analysis results, dynamic linking between plots and code tracking for reproducibility. We demonstrate the utility and flexibility of iSEE by applying it to explore a range of real transcriptomics and proteomics data sets.

Indexed as

BioconductorgenomicsinteractiveproteomicsRshinytranscriptomicsvisualization

Identifiers

PMID30002819
PMCPMC6013759

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.