ArticleClinical and translational allergy2018
Severity of allergic rhinitis impacts sleep and anxiety: results from a large Spanish cohort.
Article in Clinical and translational allergy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Determinants and relationships of climate change, climate change hazards, mental health, and well-being: a systematic review.Frontiers in psychiatry · 2025Pooled it
- The Impact of Allergic Rhinitis on Australian Adults in an Urban Setting: A Qualitative Exploration.Journal of clinical medicine · 2026Article
- Article
- Clinical and Healthcare Cost Characteristics of Severe Asthma Patients with Long-Term Control on Omalizumab: A Comparative Analysis with Patients Who Switched to Other Biologics.Journal of asthma and allergy · 2025Article
- Pollen effects in a changing climate: Ragweed pollen exposure and sleepiness in immunotherapy patients of a Southeastern Michigan allergy clinic.International journal of biometeorology · 2024Article
- Association between allergic diseases, generalized anxiety disorder, and depressive symptoms in South Korean adolescents: a secondary data analysis of the 2022 Korea Youth Risk Behavior Survey.Child health nursing research · 2024Article
- TET2 deficiency promotes anxiety and depression-like behaviors by activating NLRP3/IL-1β pathway in microglia of allergic rhinitis mice.Molecular medicine (Cambridge, Mass.) · 2023Article
- Anxiety in adults with asthma during the coronavirus disease 2019 pandemic: a Canadian perspective.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023Article
- Exploring the latest understanding on the role of immune mediators, genetic and environmental factors in pathogenesis of allergic rhinitis: a systematic review.Frontiers in allergy · 2023Review
- Psychological Disorders of Patients With Allergic Rhinitis in Chengdu, China: Exploratory Research.JMIR formative research · 2022Article
- Management of allergic rhinitis symptoms in the pharmacy Pocket guide 2022.Clinical and translational allergy · 2022Article
- Sleep, Fatigue, and Depressive Symptoms among Female Nurses with Allergic Rhinitis.Healthcare (Basel, Switzerland) · 2021Article
- Validity, reliability, and responsiveness of daily monitoring visual analog scales in MASK-air®.Clinical and translational allergy · 2021Review
- Seasonal Variation in Generic and Disease-Specific Health-Related Quality of Life in Rhinologic Patients in Southern Finland.International journal of environmental research and public health · 2021Article
- Allergic Rhinitis and Depression: Profile and Proposal.Frontiers in psychiatry · 2021Review
- Case Report: Off-Label Use of Omalizumab in a 6-Year-Old Boy With ASD Ameliorated Severe Allergic Rhinitis and Subsequently Improved Behavioral Symptoms.Frontiers in pediatrics · 2021Article
- Efficacy and Safety of Guizhi Decoction AssociatedFormulas for Allergic Rhinitis: A Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2021Review
- Treatment of allergic rhinitis during and outside the pollen season using mobile technology. A MASK study.Clinical and translational allergy · 2020Review
- Determinants of the utilization of allergy management measures among hay fever sufferers: a theory-based cross-sectional study.BMC public health · 2020Article
- Psychological profiles of patients with suspected drug allergy.Asia Pacific allergy · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAllergic rhinitis (AR) is a highly prevalent disease that generates high social and health care costs and also has a significant effect on quality of life and quality of sleep. It has also been related to some psychological disorders like anxiety or depression.
objectiveTo evaluate anxiety, depression, and quality of sleep and life alteration in a group of patients with perennial AR compared to a group of seasonal AR patients.
methodsSix-hundred seventy adults (> 18 years) with perennial and seasonal AR were recruited consecutively in 47 centers in Spain. Individuals were grouped in "Perennial" and "Seasonal" according to the seasonality of their symptoms. Anxiety, depression, sleep quality and health related quality of life were evaluated using the Hospital Anxiety and Depression Scale, Medical Outcomes Study Sleep Scale (MOS Sleep Scale) and the Health-related quality of life questionnaire ESPRINT-15, respectively. Both groups of patients were evaluated in and out of the pollen season.
resultsAR symptoms are related to worse quality of life and more anxiety and depression symptoms. Indeed, symptom severity also correlates with worse outcomes (quality of life, sleep and depression/anxiety) regardless allergen seasonality. Symptoms severity, compared with seasonality and persistence, is the most important factor related with more anxiety and depression and poor sleep. However, symptoms severity, persistence and seasonality are independently affecting the quality of life in patients with AR.
conclusionsAlthough AR symptoms have a great impact on depression and anxiety symptoms, quality of life and quality of sleep in all AR patients, as expected, individuals with more severe AR seem to suffer more intensely their effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.