Evidence map›Paper›PMID 30002717›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

Ingestion of Exopolymers from

Jong-Min Lim, Eunju Do, Dong-Chan Park, Go-Woon Jung, Hyung-Rae Cho, Seo-Young Lee, Jae Wook Shin, Kyung Min Baek, Jae-Suk Choi

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jong-Min LimGlucan Corp., #305 Marine Bio-Industry Development Center, 7 Hoenggye-gil, Ilgwang-myeon, Busan 46048, Republic of Korea.
Eunju DoKorean Medicine Industry Support Center, Daegu Technopark, 136 Sincheondong-ro, Suseong-gu, Daegu 42158, Republic of Korea.
Dong-Chan ParkGlucan Corp., #305 Marine Bio-Industry Development Center, 7 Hoenggye-gil, Ilgwang-myeon, Busan 46048, Republic of Korea.
Go-Woon JungGlucan Corp., #305 Marine Bio-Industry Development Center, 7 Hoenggye-gil, Ilgwang-myeon, Busan 46048, Republic of Korea.
Hyung-Rae ChoGlucan Corp., #305 Marine Bio-Industry Development Center, 7 Hoenggye-gil, Ilgwang-myeon, Busan 46048, Republic of Korea.
Seo-Young LeeKorean Medicine Industry Support Center, Daegu Technopark, 136 Sincheondong-ro, Suseong-gu, Daegu 42158, Republic of Korea.
Jae Wook ShinDepartment of Korean Medicine for Internal Medicine, Daegu Korean Medicine Hospital of Daegu Haany University, 136 Sincheondong-ro, Suseong-gu, Daegu 42158, Republic of Korea.
Kyung Min BaekDepartment of Korean Medicine for Internal Medicine, Daegu Korean Medicine Hospital of Daegu Haany University, 136 Sincheondong-ro, Suseong-gu, Daegu 42158, Republic of Korea.ORCID 0000-0002-9898-7987
Jae-Suk ChoiMajor in Food Biotechnology, Division of Bioindustry, College of Medical and Life Sciences, Silla University, 140, Baegyang-daero 700beon-gil, Sasang-gu, Busan 46958, Republic of Korea.ORCID 0000-0002-8151-6054

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe objective of the study was to assess the efficacy of exopolymers from

methodsWe conducted a randomized, double-blind, placebo-controlled study at the onset of the influenza season. A total of 76 subjects (30-70 years of age) were recruited from the general population. The subjects were instructed to take one capsule per day of either EAP or a placebo for a period of 8 weeks. The duration of cold and flu symptoms, a primary variable in assessing effectiveness, and serum cytokine levels as well as WBC counts as secondary variables were also evaluated.

resultsEAP was associated with a statistically significant decrease in the duration of cold and flu symptoms, a primary variable in assessing effectiveness. Although cold and flu symptom levels were not significantly different at a significance level of 5%, the cold and flu symptom levels of the EAP group were less severe compared to the placebo group. No statistically significant changes of serum cytokine levels as well as WBC counts were observed.

conclusionThe results showed that EAP is a useful pharmaceutical and functional food material for preventing and treating colds and flu.

Identifiers

PMID30002717
PMCPMC5998159

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.