Evidence map›Paper›PMID 30002707›Full record

ArticleArchives of medical science : AMS2018

Effectiveness of median nerve neural mobilization versus oral ibuprofen treatment in subjects who suffer from cervicobrachial pain: a randomized clinical trial.

David Rodriguez Sanz, Francisco Unda Solano, Daniel López López, Irene Sanz Corbalan, Carlos Romero Morales, Cesar Calvo Lobo

6 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02593721 phase2 / phase3completednot on this map

Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain

TypeinterventionalSponsorUniversidad Europea de MadridRan2015 to 2015Enrolled50ConditionsCervicobrachial NeuralgiaArmsMedian Nerve Neural Mobilization, Ibuprofen
NCT04025203 phase4completednot on this mapstarted 2019, after this paper: background citation

Pain Reduction and Changes in Upper Limb Function Produced by Physiotherapy, Ibuprofen Arginine, Gabapentin and the Absence of Treatment, in Carpal Tunnel Syndrome

TypeinterventionalSponsorFrancisco Unda SolanoRan2019 to 2019Enrolled196ConditionsCarpal Tunnel SyndromeArmsMedian nerve neural mobilization, Ibuprofen Arginine, Gabapentin
NCT04119739 phase4completednot on this mapstarted 2020, after this paper: background citation

Pain Reduction Produced by Physiotherapy, Ibuprofen Arginine, and the Absence of Treatment, in Carpal Tunnel Syndrome

TypeinterventionalSponsorFrancisco Unda SolanoRan2020 to 2020Enrolled117ConditionsCarpal Tunnel SyndromeArmsMedian nerve neural mobilization, Ibuprofen Arginine
NCT04285281 phase4completednot on this mapstarted 2020, after this paper: background citation

Oral Gabapentin and Median Nerve Neural Mobilization Versus Control in the Treatment of Carpal Tunnel Syndrome

TypeinterventionalSponsorUniversidad Europea de MadridRan2020 to 2020Enrolled126ConditionsCarpal Tunnel SyndromeArmsGabapentin oral capsules, Median nerve neural mobilization
NCT04329247 nacompletednot on this mapstarted 2020, after this paper: background citation

Physical Therapy Versus Control in the Treatment of Carpal Tunnel Syndrome

TypeinterventionalSponsorUniversidad Europea de MadridRan2020 to 2020Enrolled74ConditionsCarpal Tunnel SyndromeArmsMedian nerve neural mobilization
NCT04652934 nacompletednot on this mapstarted 2022, after this paper: background citation

Effectiveness of the Neural Mobilization on Upper Limb Functionality in Patients With Acquired Brain Injury: Randomized, Controlled, Multi-Centric, Single-Blind Clinical Trial

TypeinterventionalSponsorVanesa AbuínRan2022 to 2023Enrolled24ConditionsHemiplegia and Hemiparesis, Acquired Brain InjuryArmsNeurodynamic, Mimic group
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

David Rodriguez SanzDepartment of Physical Therapy and Podiatry, Physical Therapy and Health Sciences Research Group Universidad Europea de Madrid, Madrid, Spain.
Francisco Unda SolanoInteruniversity Degree in Physiotherapy UB-UdG/Grau en Fisioteràpia EUSES-UdG, Barcelona, Spain.
Daniel López LópezResearch, Health and Podiatry Unit, Department of Health Sciences, Faculty of Nursing and Podiatry, Universidade da Coruña, Spain.
Irene Sanz CorbalanDepartment of Nursing, Physical Therapy and Podiatry, Universidad Complutense de Madrid, Madrid, Spain.
Carlos Romero MoralesDepartment of Physical Therapy and Podiatry, Physical Therapy and Health Sciences Research Group Universidad Europea de Madrid, Madrid, Spain.
Cesar Calvo LoboNursing and Physical Therapy Department, Institute of Biomedicine (IBIOMED), Universidad de Leon, Leon, Spain.
Universidad Europea de Madrid · ESUniversidad Complutense de Madrid · ESUniversidad de León · ESUniversidade da Coruña · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOral ibuprofen (OI) and median nerve neural mobilization (MNNM) are first line treatments for patients who suffer cervicobrachial pain (CP). OI may produce side effects which are not tolerated by all subjects who suffer CP, whereas MNNM has no known side effects. Therefore, the aim of this study was to assess the effectiveness of both treatments (OI vs. MNNM) in CP. MATERIAL AND

methodsThis investigation was a blinded parallel randomized clinical trial (NCT02593721). Sixty-two participants diagnosed with CP were recruited and randomly assigned to 2 groups (

resultsThe results showed that OI treatment (η

conclusionsOral ibuprofen may be superior to MNNM for pain reduction and upper limb function increase of subjects with CP. Nevertheless, both treatments were effective. Median nerve neural mobilization may be considered an effective non-pharmaceutical treatment option in subjects with CP. Regarding OI adverse effects, our findings challenge the role of pharmacologic versus manual therapy as possible treatments that may improve pain intensity and upper limb functionality in subjects with CP.

Indexed as

musculoskeletal manipulationsnon-steroidal anti-inflammatory agentsrehabilitationupper extremity

Identifiers

PMID30002707
PMCPMC6040136
OpenAlexW2765343771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.