Evidence map›Paper›PMID 30002468›Full record

ArticleScientific reports2018

Relation of Prenatal Air Pollutant and Nutritional Exposures with Biomarkers of Allergic Disease in Adolescence.

Joanne E Sordillo, Karen M Switkowski, Brent A Coull, Joel Schwartz, Itai Kloog, Heike Gibson, Augusto A Litonjua, Jennifer Bobb, Petros Koutrakis, Sheryl L Rifas-Shiman and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Maternal Dietary Factors and the Risk of Autism Spectrum Disorders: A Systematic Review of Existing Evidence.Autism research : official journal of the International Society for Autism Research · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Joanne E SordilloDivision of Chronic Disease Research Across the Lifecourse (CoRAL), Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Karen M SwitkowskiDivision of Chronic Disease Research Across the Lifecourse (CoRAL), Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Brent A CoullDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Joel SchwartzDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Itai KloogDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Heike GibsonDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Augusto A LitonjuaDivision of Pediatric Pulmonary Medicine, University of Rochester Medical Center, Rochester, NY, USA.
Jennifer BobbKaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Petros KoutrakisDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Sheryl L Rifas-ShimanDivision of Chronic Disease Research Across the Lifecourse (CoRAL), Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Emily OkenDivision of Chronic Disease Research Across the Lifecourse (CoRAL), Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Diane R GoldDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA. redrg@channing.harvard.edu.
Harvard University · USBrigham and Women's Hospital · USKaiser Permanente Washington Health Research Institute · USUniversity of Rochester Medical Center · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Prenatal environmental determinants of health in young adulthood: a lifecourse approachR01HD034568 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI Marie-France Hivert, Emily Oken · 1998 to 2026
$20.6M
Common and distinct early environmental influences on cardiometabolic and respiratory health: Mechanisms and methodsUH3OD023286 · OD · HARVARD PILGRIM HEALTH CARE, INC. · PI OKEN, EMILY · 2018 to 2022
$11.7M
Common and distinct early environmental influences on cardiometabolic and respiratory health: Mechanisms and methodsUG3OD023286 · OD · HARVARD PILGRIM HEALTH CARE, INC. · PI KLEINMAN, KENNETH P., OKEN, EMILY · 2016 to 2017
$4.1M
The Fetal and Childhood Environment, Oxidative Balance, Inflammation and AsthmaR01AI102960 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLD, DIANE R, OKEN, EMILY · 2013 to 2017
$4.0M
Age-Dependent Pharmacogenomics of Asthma Treatment (ADAPT)R01HD085993 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI WU, ANN CHEN · 2016 to 2020
$3.1M
NIAID NIH HHS R01 AI102960NICHD NIH HHS R01 HD034568NICHD NIH HHS R01 HD085993NIEHS NIH HHS P30 ES000002NIH HHS UG3 OD023286NIH HHS UH3 OD023286
6 · The paper itself

Abstract

Prenatal exposures may be critical for immune system development, with consequences for allergic disease susceptibility. We examined associations of prenatal exposures (nutrient intakes and air pollutants) with allergic disease biomarkers in adolescence. We used data from 857 mother-child pairs in Project Viva, a Massachusetts-based pre-birth cohort. Outcomes of interest at follow-up (median age 12.9 years) were fractional exhaled nitric oxide (FeNO) and total serum IgE. We applied Bayesian Kernel Machine Regression analyses to estimate multivariate exposure-response functions, allowing for exposure interactions. Exposures were expressed as z-scores of log-transformed data and we report effects in % change in FeNO or IgE z-score per increase in exposure from the 25

Indexed as

AdolescentAir PollutantsAir PollutionBayes TheoremBiomarkersBreath TestsChildDietary SupplementsEnvironmental ExposureFemaleFollow-Up StudiesHumansHypersensitivityImmunoglobulin ELongitudinal StudiesMaleAir PollutantsBiomarkersImmunoglobulin ENitric OxideVitamin E

Identifiers

PMID30002468
PMCPMC6043562
OpenAlexW2846981597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.