Evidence map›Paper›PMID 30002324›Full record

ArticleJournal of functional biomaterials2018

Interconnected PolymerS TeChnology (IPSTiC): An Effective Approach for the Modulation of 5α-Reductase Activity in Hair Loss Conditions.

Ortensia Ilaria Parisi, Luca Scrivano, Fabio Amone, Rocco Malivindi, Mariarosa Ruffo, Anna Francesca Vattimo, Vincenzo Pezzi, Francesco Puoci

Open access · goldAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ortensia Ilaria ParisiDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy. ortensiailaria.parisi@unical.it.ORCID 0000-0002-2556-9864
Luca ScrivanoDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy. luca.scrivano@unical.it.ORCID 0000-0003-3773-5492
Fabio AmoneMacrofarm s.r.l., c/o Department of Pharmacy, Health and Nutrition Sciences, University of Calabria, 87036 Rende (CS), Italy. amonefabio@gmail.com.
Rocco MalivindiDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy. rocco.malivindi@unical.it.ORCID 0000-0002-8313-2492
Mariarosa RuffoDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy. mariarosaruffo8@gmail.com.ORCID 0000-0002-8878-3702
Anna Francesca VattimoMacrofarm s.r.l., c/o Department of Pharmacy, Health and Nutrition Sciences, University of Calabria, 87036 Rende (CS), Italy. vattimoanna@yahoo.it.
Vincenzo PezziDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy. v.pezzi@unical.it.
Francesco PuociDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy. francesco.puoci@unical.it.ORCID 0000-0002-5963-6762
University of Calabria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hair loss represents a condition that adversely affects the social life of patients. The most common cause is androgenetic alopecia (AGA), which is a genetically determined progressive hair-loss condition involving 5α-reductase. In this study, a novel anti-baldness agent based on Interconnected PolymerS TeChnology (IPSTiC), which is an effective strategy for the delivery of bioactive molecules, was developed. This product (IPSTiC patch hair) is based on a polymeric blend consisting of high molecular weight hyaluronic acid and soybean proteins and is able to improve efficacy and stability of bioactive ingredients such as

Indexed as

5α-reductaseandrogenetic alopecia (AGA)Camellia Sinensis leaf extractCapsicum Annuum fruit extractEPISKIN modelhair losshyaluronic acidOriganum vulgare leaf extractpolymeric blendsoybean proteins

Identifiers

PMID30002324
PMCPMC6163819
OpenAlexW2854924783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.