Evidence map›Paper›PMID 30002323›Full record

Trial reportNutrients2018

A Vegetarian Diet Is a Major Determinant of Gut Microbiota Composition in Early Pregnancy.

Helen L Barrett, Luisa F Gomez-Arango, Shelley A Wilkinson, H David McIntyre, Leonie K Callaway, Mark Morrison, Marloes Dekker Nitert

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 4 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 4 syntheses or guidelines pooled it, 125 citations in OpenAlex.

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  4. The role of gut micorbiome in obesity and diabetes.World journal of pediatrics : WJP · 2019
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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Helen L BarrettDepartment of Endocrinology, Mater Health, South Brisbane, QLD 4101, Australia. helen.barrett@mater.uq.edu.au.
Luisa F Gomez-ArangoSchool of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD 4072, Australia. luisa.gomezarango@uq.net.au.
Shelley A WilkinsonDepartment of Endocrinology, Mater Health, South Brisbane, QLD 4101, Australia. shelley.wilkinson@mater.org.au.
H David McIntyreMater Research Institute, University of Queensland, South Brisbane, QLD 4101, Australia. david.mcintyre@mater.org.au.
Leonie K CallawayDepartment of Obstetric Medicine, Royal Brisbane and Women's Hospital, Herston, QLD 4059, Australia. Leonie.Callaway@health.qld.gov.au.
Mark MorrisonDiamantina Institute, Faculty of Medicine, The University of Queensland, Translational Research Institute, Woolloongabba, QLD 4102, Australia. m.morrison1@uq.edu.au.
Marloes Dekker NitertSchool of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD 4072, Australia. m.dekker@uq.edu.au.ORCID 0000-0002-1909-8920
The University of Queensland · AUMater Health Services · AUTranslational Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The composition of the gut microbiota can be influenced by dietary composition. In pregnancy, the maternal gut microbiome has associations with maternal and infant metabolic status. There is little known regarding the impact of a vegetarian diet in pregnancy on maternal gut microbiota. This study explored the gut microbiota profile in women who were vegetarian or omnivorous in early gestation. Women were selected from participants in the Study of PRobiotics IN Gestational diabetes (SPRING) randomised controlled trial. Nine women identified as vegetarians were matched to omnivorous women in a 1:2 ratio. Microbiota analyses were performed using 16S rRNA gene amplicon sequencing and analysed using the Quantitative Insights Into Microbial Ecology (QIIME) and Calypso software tools. There was no difference in alpha diversity, but beta diversity was slightly reduced in vegetarians. There were differences seen in the relative abundance of several genera in those on a vegetarian diet, specifically a reduction in

Indexed as

Diet, VegetarianGastrointestinal MicrobiomeMaternal Nutritional Physiological PhenomenaAdultDigestionFemaleFermentationGastrointestinal TractGestational AgeHumansNutritional StatusNutritive ValueObesityPregnancyPreliminary DataProbioticsmicrobiotapregnancyvegetarian

Identifiers

PMID30002323
PMCPMC6073691
OpenAlexW2815780128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.