Evidence map›Paper›PMID 30002285›Full record

ArticleInternational journal of molecular sciences2018

Allyl Isothiocyanate Ameliorates Dextran Sodium Sulfate-Induced Colitis in Mouse by Enhancing Tight Junction and Mucin Expression.

Min Woo Kim, Seungho Choi, Sun Yeou Kim, Yeo Sung Yoon, Ju-Hee Kang, Seung Hyun Oh

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. The Anti-AGEing and RAGEing Potential of Isothiocyanates.Molecules (Basel, Switzerland) · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Wasabi (Foods (Basel, Switzerland) · 2022
    Article
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  16. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Min Woo KimDepartment of Anatomy and Cell Biology, College of Veterinary Medicine, Seoul National University, 08826 Seoul, Korea. eastsea1203@gmail.com.ORCID 0000-0002-6597-4522
Seungho ChoiDepartment of Anatomy and Cell Biology, College of Veterinary Medicine, Seoul National University, 08826 Seoul, Korea. schoi790227@gmail.com.
Sun Yeou KimGachon Institute of Pharmaceutical Sciences, Gachon University, 21936 Incheon, Korea. sunnykim@gachon.ac.kr.ORCID 0000-0001-8044-5613
Yeo Sung YoonDepartment of Anatomy and Cell Biology, College of Veterinary Medicine, Seoul National University, 08826 Seoul, Korea. ysyoon@snu.ac.kr.
Ju-Hee KangGachon Institute of Pharmaceutical Sciences, Gachon University, 21936 Incheon, Korea. applekjh0503@hanmail.net.ORCID 0000-0002-0192-6310
Seung Hyun OhGachon Institute of Pharmaceutical Sciences, Gachon University, 21936 Incheon, Korea. eyeball@hanmail.net.ORCID 0000-0003-3678-2772
Gachon University · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is characterized by chronic or recurrent inflammation of the gastrointestinal tract. Even though the current strategies to treat IBD include anti-inflammatory drugs and immune modulators, these treatments have side-effects. New strategies are, therefore, required to overcome the limitations of the therapies. In this study, we investigated the anti-colitic effects of allyl isothiocyanate (AITC), which is an active ingredient present in

Indexed as

Inflammatory Bowel DiseasesAnimalsCaco-2 CellsDextran SulfateFemaleGene Expression RegulationHumansIsothiocyanatesLipopolysaccharidesMAP Kinase Signaling SystemMiceMucin-2RAW 264.7 CellsTight JunctionsWasabiaallyl isothiocyanateDextran SulfateIsothiocyanateslipopolysaccharide, Escherichia coli O111 B4LipopolysaccharidesMUC2 protein, humanMuc2 protein, mouseMucin-2allyl isothiocyanate (AITC)colitisdextran sodium sulfate (DSS)goblet cellintestinal epithelial barriermucinmucin 2 (MUC2)tight junctionWasabia japonica

Identifiers

PMID30002285
PMCPMC6073867
OpenAlexW2840707404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.