ArticleSensors (Basel, Switzerland)2018
Graphene-Based Raman Spectroscopy for pH Sensing of X-rays Exposed and Unexposed Culture Media and Cells.
Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Highly Sensitive TiOBiosensors · 2022Article
- Highly Stable, Graphene-Wrapped, Petal-like, Gap-Enhanced Raman Tags.Nanomaterials (Basel, Switzerland) · 2022Article
- Properties and Applications of Graphene and Its Derivatives in Biosensors for Cancer Detection: A Comprehensive Review.Biosensors · 2022Review
- Advanced Optical Sensing of Phenolic Compounds for Environmental Applications.Sensors (Basel, Switzerland) · 2021Review
- Graphene-Based and Surface-Enhanced Raman Spectroscopy for Monitoring the Physio-Chemical Response of Thermophilic Bacterial Spores to Low Temperatures Exposure.Sensors (Basel, Switzerland) · 2020Article
- Multivariate Analysis of Difference Raman Spectra of the Irradiated Nucleus and Cytoplasm Region of SH-SY5Y Human Neuroblastoma Cells.Sensors (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
Graphene provides a unique way of sensing the local pH level of substances on the micrometric scale, with important implications for the monitoring of cellular metabolic activities where proton excretion could occur. Accordingly, an innovative biosensing approach for the quantification of the pH value of biological fluids, to be used also with small amounts of fluids, was realized and tested. It is based on the use of micro-Raman spectroscopy to detect the modifications of the graphene doping level induced by the contact of the graphene with the selected fluids. The approach was preliminarily tested on aqueous solutions of known pH values. It was then used to quantify the pH values of cell culture media directly exposed to different doses of X-ray radiation and to media exposed to X-ray-irradiated cells. The Raman response of cells placed on graphene layers was also examined.
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Registered trials
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