Evidence map›Paper›PMID 30002222›Full record

ArticleJournal of the American Society of Nephrology : JASN2018

The Human FSGS-Causing

Gentzon Hall, Brandon M Lane, Kamal Khan, Igor Pediaditakis, Jianqiu Xiao, Guanghong Wu, Liming Wang, Maria E Kovalik, Megan Chryst-Stangl, Erica E Davis and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 88 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Gentzon HallDepartments of Pediatrics and.
Brandon M LaneDepartments of Pediatrics and.
Kamal KhanCenter for Human Disease Modeling, Duke University Medical Center, Durham, North Carolina.ORCID 0000-0002-8366-4237
Igor PediaditakisCenter for Human Disease Modeling, Duke University Medical Center, Durham, North Carolina.
Jianqiu XiaoCenter for Human Disease Modeling, Duke University Medical Center, Durham, North Carolina.
Guanghong WuDepartments of Pediatrics and.
Liming WangMedicine, Duke University School of Medicine, Durham, North Carolina.
Maria E KovalikDepartments of Pediatrics and.
Megan Chryst-StanglDepartments of Pediatrics and.
Erica E DavisDepartments of Pediatrics and.
Robert F SpurneyMedicine, Duke University School of Medicine, Durham, North Carolina.
Rasheed A GbadegesinDepartments of Pediatrics and rasheed.gbadegesin@duke.edu.ORCID 0000-0001-5641-6644
Duke University · USDuke Medical Center · USPediatrics and Genetics · US

Funding

Renal Genomics CoreP30DK096493 · NIDDK · DUKE UNIVERSITY · PI FOSTER, MARY H., SVETKEY, LAURA P · 2012 to 2016
$5.9M
DUKE TRAINING GRANT IN NEPHROLOGYT32DK007731 · NIDDK · DUKE UNIVERSITY · PI CROWLEY, STEVEN D · 1995 to 2021
$3.6M
Functional and Phenotypic Characterization of a New FSGS GeneR01DK098135 · NIDDK · DUKE UNIVERSITY · PI GBADEGESIN, RASHEED ADEBAYO · 2014 to 2018
$1.8M
Role of Gq Signaling in Promoting Podocyte Injury in Diabetes MellitusR01DK087707 · NIDDK · DUKE UNIVERSITY · PI SPURNEY, ROBERT · 2011 to 2014
$1.4M
The Role of Interleukin-15 Receptor-alpha Variants in the Pathogenesis of FSGSK08DK111940 · NIDDK · DUKE UNIVERSITY · PI HALL, GENTZON · 2017 to 2021
$794k
Novel Targets for the Treatment of Diabetic Kidney DiseaseI01BX002984 · VA · DURHAM VA MEDICAL CENTER · PI SPURNEY, ROBERT · 2016 to 2019
–
BLRD VA I01 BX002984NIDDK NIH HHS K08 DK111940NIDDK NIH HHS P30 DK096493NIDDK NIH HHS R01 DK087707NIDDK NIH HHS R01 DK098135NIDDK NIH HHS T32 DK007731
6 · The paper itself

Abstract

backgroundWe previously reported that mutations in the anillin (

methodsWe conducted

resultsExperiments in

conclusionsThe

Indexed as

AnimalsApoptosisCell MovementCells, CulturedGene Expression RegulationGlomerulosclerosis, Focal SegmentalHumansMicrofilament ProteinsMutation, MissensePhosphatidylinositol 3-KinasesPodocytesProto-Oncogene Proteins c-aktrac1 GTP-Binding ProteinSensitivity and SpecificitySignal TransductionTOR Serine-Threonine KinasesANLN protein, humanMicrofilament ProteinsMTOR protein, humanPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktrac1 GTP-Binding ProteinRAC1 protein, humanTOR Serine-Threonine KinasesAKTANILLINER-STRESSfocal segmental glomerulosclerosisMTORRAC1

Identifiers

PMID30002222
PMCPMC6065096
OpenAlexW2841355558

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.