Evidence map›Paper›PMID 30002215›Full record

ReviewBMJ case reports2018

Neutropaenia and splenomegaly without arthritis: think rheumatoid arthritis.

Fawad Aslam, Rabia S Cheema, Michael Feinstein, April Chang-Miller

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Fawad AslamDepartment of Rheumatology, Mayo Clinic Arizona, Scottsdale, Arizona, USA.ORCID http://orcid.org/0000-0001-6016-6123
Rabia S CheemaInternal Medicine, St. Mary's Hospital, Waterbury, Connecticut, USA.
Michael FeinsteinDepartment of Hematology and Oncology, Mayo Clinic Arizona, Scottsdale, Arizona, USA.
April Chang-MillerDepartment of Rheumatology, Mayo Clinic Arizona, Scottsdale, Arizona, USA.
Mayo Clinic in Arizona · USSt. Mary’s Hospital · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Felty syndrome(FS) is an uncommon, but severe, extra-articular manifestation of rheumatoid arthritis (RA). It occurs in patients with longstanding RA. It is extremely rare for RA to present as FS or develop after initially presenting as neutropaenia and splenomegaly. We describe a case of 47-year-old woman who was diagnosed simultaneously with FS and possible RA after testing positive for anticyclic citrullinated peptide antibody, but a negative rheumatoid factor. She had an excellent response to methotrexate. We review the existing literature of such cases and emphasise the importance of serological testing for RA in patients presenting with neutropaenia and splenomegaly, even in the absence of joint symptoms or prior diagnosis of RA.

Indexed as

Arthritis, RheumatoidAutoantibodiesDiagnosis, DifferentialFelty SyndromeFemaleHumansMiddle AgedNeutropeniaPeptides, CyclicRheumatoid FactorSplenomegalyAutoantibodiesPeptides, CyclicRheumatoid Factorhaematology (incl blood transfusion)rheumatoid arthritis

Identifiers

PMID30002215
PMCPMC6047694
OpenAlexW2844879593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.