Evidence map›Paper›PMID 30002140›Full record

Observational studyCirculation. Cardiovascular quality and outcomes2018

Adapting and Evaluating a Health System Intervention From Kaiser Permanente to Improve Hypertension Management and Control in a Large Network of Safety-Net Clinics.

Valy Fontil, Reena Gupta, Nathalie Moise, Ellen Chen, David Guzman, Charles E McCulloch, Kirsten Bibbins-Domingo

Open access · bronzeAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Circulation. Cardiovascular quality and outcomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

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  8. Lived experience of people with hypertension in Ethiopia: A phenomenological study, 2025.American heart journal plus : cardiology research and practice · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Valy FontilDivision of General Internal Medicine, Zuckerberg San Francisco General Hospital (V.F., R.G., D.G., K.B.-D.) valy.fontil@ucsf.edu.
Reena GuptaDivision of General Internal Medicine, Zuckerberg San Francisco General Hospital (V.F., R.G., D.G., K.B.-D.).
Nathalie MoiseDepartment of Medicine, Columbia University Medical Center, New York, NY (N.M.).
Ellen ChenSan Francisco Department of Public Health, CA (E.C.).
David GuzmanDivision of General Internal Medicine, Zuckerberg San Francisco General Hospital (V.F., R.G., D.G., K.B.-D.).
Charles E McCulloch
Kirsten Bibbins-DomingoDivision of General Internal Medicine, Zuckerberg San Francisco General Hospital (V.F., R.G., D.G., K.B.-D.).
San Francisco General Hospital · US

Funding

The Discovering Healthcare Innovations to Address Disparties in Stroke (DIADS) prU54NS081760 · NINDS · KAISER FOUNDATION RESEARCH INSTITUTE · PI BIBBINS-DOMINGO, KIRSTEN · 2012 to 2016
$10.5M
Hypertension Management in Minority and Low-income PopulationsK24DK103992 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BIBBINS-DOMINGO, KIRSTEN · 2014 to 2018
$917k
Bring it Down San Francisco: Harnessing cloud-based technology to improve hypertension management in a low-income underserved populationK23HL136899 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FONTIL, VALY · 2018 to 2022
$887k
NHLBI NIH HHS K23 HL136899NIDDK NIH HHS K24 DK103992NINDS NIH HHS U54 NS081760
6 · The paper itself

Abstract

backgroundNearly half of Americans with diagnosed hypertension have uncontrolled blood pressure (BP) while some integrated healthcare systems, such as Kaiser Permanente Northern California, have achieved control rates upwards 90%. METHODS AND

resultsWe adapted Kaiser Permanente's evidence-based treatment protocols in a racially and ethnically diverse population at 12 safety-net clinics in the San Francisco Health Network. The intervention consisted of 4 elements: a hypertension registry, a simplified treatment intensification protocol that included fixed-dose combination medications containing diuretics, standardized BP measurement protocol, and BP check visits led by registered nurse and pharmacist staff. The study population comprised patients with hypertension who made ≥1 primary care visits within the past 24 months (n=15 917) and had a recorded BP measurement within the past 12 months. We conducted a postintervention time series analysis from August 2014 to August 2016 to assess the effect of the intervention on BP control for 24 months for the pilot site and for 15 months for 11 other San Francisco Health Network clinics combined. Secondary outcomes were changes in use of guideline-recommended medication prescribing. Rates of BP control increased at the pilot site (68%-74%;

conclusionsEvidence-based system approaches to improving BP control can be implemented in safety-net settings and could play a pivotal role in achieving improved population BP control and reducing hypertension disparities.

Indexed as

AdultAgedAged, 80 and overAntihypertensive AgentsBlood PressureDelivery of Health Care, IntegratedDrug CombinationsEvidence-Based MedicineFemaleGuideline AdherenceHealthcare DisparitiesHealth Maintenance OrganizationsHealth Systems PlansHumansHypertensionMaleAntihypertensive AgentsDrug Combinationsblood pressureethnichypertensionsafety-net providers

Identifiers

PMID30002140
PMCPMC6071320
OpenAlexW2813469675

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.