Evidence map›Paper›PMID 30002130›Full record

ArticleDevelopment (Cambridge, England)2018

Histone deacetylase activity has an essential role in establishing and maintaining the vertebrate neural crest.

Anjali Rao, Carole LaBonne

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Screening H3 Histone Acetylation in a Wild Bird, the House Sparrow (Integrative organismal biology (Oxford, England) · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Epigenomic dynamics of early Xenopus Embryos.Development, growth & differentiation · 2022
    Review
  12. Review
  13. Neuronal lineages derived from the nerve-associated Schwann cell precursors.Cellular and molecular life sciences : CMLS · 2021
    Review
  14. Chemical-induced craniofacial anomalies caused by disruption of neural crest cell development in a zebrafish model.Developmental dynamics : an official publication of the American Association of Anatomists · 2020
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anjali RaoDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.
Carole LaBonneDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA clabonne@northwestern.edu.ORCID 0000-0001-6001-7179
Northwestern University · US

Funding

Neural Crest Ontogeny and the Control of Stem Cell AttributesR01GM116538 · NIGMS · NORTHWESTERN UNIVERSITY · PI LABONNE, CAROLE · 2015 to 2018
$1.2M
NIGMS NIH HHS R01 GM116538
6 · The paper itself

Abstract

The neural crest, a progenitor population that drove vertebrate evolution, retains the broad developmental potential of the blastula cells it is derived from, even as neighboring cells undergo lineage restriction. The mechanisms that enable these cells to preserve their developmental potential remain poorly understood. Here, we explore the role of histone deacetylase (HDAC) activity in this process in

Indexed as

AcetylationAnimalsBiomarkersBlastulaCell LineageEmbryo, NonmammalianGene Expression Regulation, DevelopmentalHistone Deacetylase 1Histone Deacetylase InhibitorsHistonesNeural CrestPluripotent Stem CellsXenopus laevisXenopus ProteinsBiomarkersHDAC1 protein, XenopusHistone Deacetylase 1Histone Deacetylase InhibitorsHistonesXenopus ProteinsHDACHistone acetylationNeural crestPluripotencyStem cellXenopus

Identifiers

PMID30002130
PMCPMC6110147
OpenAlexW2868964760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.