ArticleCanadian family physician Medecin de famille canadien2018
Large pertussis outbreak in rural Canada: Lessons learned from Haida Gwaii.
Article in Canadian family physician Medecin de famille canadien, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Global, regional, and national burden of pertussis in children aged 0-14 years from 1990 to 2021: A systematic analysis of the Global Burden of Disease Study 2021.Infectious diseases & immunity · 2026Article
- Pertussis Outbreak Investigation in a Korean Middle School: Insights on Tdap and Td Vaccination.Journal of Korean medical science · 2026Article
- Pertussis outbreak investigation in Likimsa-BokoreThe Pan African medical journal · 2024Article
- Structure and Immunogenicity of theVaccines · 2021Article
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Authors and funding
4 authors.
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Abstract
objectiveTo present characteristics of and response to a large outbreak of pertussis on Haida Gwaii, BC, in 2014.
designQuantitative descriptive review.
settingHaida Gwaii, a remote island archipelago located 100 km off of British Columbia's west coast.
participantsAll patients presenting with symptoms evaluated for pertussis on Haida Gwaii between February and August 2014.
main outcome measuresThe primary outcome measures included the demographic characteristics, time course, and morbidity of the outbreak. The secondary outcome measures included the laboratory result reports, the effects on clinician workload, and the treatment and prophylaxis practices. Statistical analysis for significance of pertussis severity and immunization status was performed with a maximum-likelihood framework.
resultsBetween February and August 2014, out of 873 clinical encounters, 579 patients were seen for pertussis-related care. Of these, 260 patients were reported to public health for case identification, contact tracing, and follow-up. There were 123 cases of probable and confirmed pertussis, a case rate of 2795 cases per 100 000 population. Of these 123 cases, 91 had a cough of more than 2 weeks' duration. A subset of patients presented with mild symptoms, atypical of pertussis. Nasopharyngeal swabs were collected on 221 occasions, 378 antibiotic prescriptions were written, and 248 prophylactic immunizations were given. The odds ratio that previous immunization protected against the development of classic pertussis was 0.23; however, statistical significance was not reached (
conclusionPertussis is resurging. Physicians need to remain vigilant for its characteristic symptoms. Clear and standardized criteria for the declaration of an outbreak should be developed. To contain an outbreak, it is crucial to deploy resources commensurate with disease activity while coordinating public health and primary care. More research into why large outbreaks continue to occur, why endemic rates continue to rise, and how these can be most effectively prevented is essential.
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