Evidence map›Paper›PMID 30001854›Full record

ReviewTrends in microbiology2018

Stable-Isotope Probing of Human and Animal Microbiome Function.

David Berry, Alexander Loy

Abstract readReview
In one paragraph

Review in Trends in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. mSystems · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Diagnosing and engineering gut microbiomes.EMBO molecular medicine · 2024
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. The exceptional form and function of the giant bacteriumProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

David BerryDivision of Microbial Ecology, Department of Microbiology and Ecosystem Science, Research Network Chemistry Meets Microbiology, University of Vienna, Althanstrasse 14, Vienna, Austria. Electronic address: berry@microbial-ecology.net.
Alexander LoyDivision of Microbial Ecology, Department of Microbiology and Ecosystem Science, Research Network Chemistry Meets Microbiology, University of Vienna, Althanstrasse 14, Vienna, Austria.

Funding

Austrian Science Fund FWF I 2320Austrian Science Fund FWF P 26127Austrian Science Fund FWF P 27831
6 · The paper itself

Abstract

Humans and animals host diverse communities of microorganisms important to their physiology and health. Despite extensive sequencing-based characterization of host-associated microbiomes, there remains a dramatic lack of understanding of microbial functions. Stable-isotope probing (SIP) is a powerful strategy to elucidate the ecophysiology of microorganisms in complex host-associated microbiotas. Here, we suggest that SIP methodologies should be more frequently exploited as part of a holistic functional microbiomics approach. We provide examples of how SIP has been used to study host-associated microbes in vivo and ex vivo. We highlight recent developments in SIP technologies and discuss future directions that will facilitate deeper insights into the function of human and animal microbiomes.

Indexed as

IsotopesAnimalsBacterial Physiological PhenomenaDNAGastrointestinal MicrobiomeHost Microbial InteractionsHumansIsotope LabelingMetagenomeMetagenomicsMolecular ProbesRNASpectrum Analysis, RamanDNAIsotopesMolecular ProbesRNAgut microbiotaNanoSIMSRaman microspectroscopyRNA-SIPsingle-cell imaging

Identifiers

PMID30001854
PMCPMC6249988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.