ReviewRheumatic diseases clinics of North America2018
Update on Sjögren Syndrome and Other Causes of Sicca in Older Adults.
Review in Rheumatic diseases clinics of North America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Association between anticholinergic activity and xerostomia and/ or xerophthalmia in the elderly: systematic review.BMC pharmacology & toxicology · 2022Pooled it
- Treatment of Sjögren's Syndrome with Mesenchymal Stem Cells: A Systematic Review.International journal of molecular sciences · 2021Pooled it
- Healthy Patients Are Not the Best Controls for Microbiome-Based Clinical Studies: Example of Sjögren's Syndrome in a Systematic Review.Frontiers in immunology · 2021Pooled it
- Laser Acupuncture on the Management of Xerostomia in Sjögren's Disease: A Randomized Clinical Trial.Oral diseases · 2026Trial
- Cutaneous Manifestations of Primary Sjögren's Syndrome: Pyoderma Gangrenosum as a Rare Initial Presentation - A Case Report and Literature Review.Annals of African medicine · 2026Review
- Oral health-related quality of life in systemic disease patients: A bibliometric analysis and visualization from 2001 to 2024.Medicine · 2026Article
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- Article
- Association between sialoscintigraphy parameters and rheumatoid factor seropositivity in patients with suspected autoimmune glandular dysfunction.Clinical and experimental medicine · 2025Article
- Salivary Biomarkers for the Diagnosis of Sjögren's Syndrome: A Review of the Last Decade.Biomedicines · 2025Review
- Ophthalmological manifestations in autoimmune diseases: Overcoming diagnostic and therapeutic challenges.World journal of experimental medicine · 2025Review
- Clinical Progress in Mesenchymal Stem Cell Therapy: A Focus on Rheumatic Diseases.Immunity, inflammation and disease · 2025Review
- Acute Kidney Injury in Autoimmune-Mediated Rheumatic Diseases.Journal of clinical medicine research · 2025Review
- Treatment of xerostomia in Sjögren's syndrome - what effect does it have on the oral microbiome?Frontiers in cellular and infection microbiology · 2025Review
- Identification of Risk Group for Root Caries and Analysis of Associated Factors in Older Adults Using Unsupervised Machine Learning Clustering.Clinical interventions in aging · 2025Article
- Evaluation of the Hypothalamic-Pituitary-Adrenal Axis in Patients with Primary Sjögren's Disease.Medicina (Kaunas, Lithuania) · 2024Article
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- Clinical characteristics of chronic sclerosing sialadenitis as a distinctive entity from primary Sjögren's syndrome.Journal of rheumatic diseases · 2024Article
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- Oral health status, related behaviours and perceived stress in xerostomia, Sicca and Sjögren's syndromes patients - a cross-sectional study.BMC oral health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Dry eye and dry mouth symptoms are each reported by up to 30% of persons more than 65 years of age, particularly in women. Medication side effects are the most common contributing factors. The evaluation of these symptoms requires measures of ocular and oral dryness. Sjögren syndrome is the prototypical disease associated with dryness of the eyes and mouth and predominantly affects women in their perimenopausal and postmenopausal years. In addition to topical treatment of the mucosal dryness, patients with Sjögren syndrome may require treatment with systemic immunomodulatory and immunosuppressive agents to manage a variety of extraglandular manifestations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.