ArticleBMC cancer2018
Distribution patterns of foot and ankle tumors: a university tumor institute experience.
Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Pooled it
- Metatarsal tumors: a comprehensive statistical overview and clinical analysis of the largest reported cohort.Skeletal radiology · 2026Review
- Distribution Patterns of Tumors and Tumor-Like Lesions of the Forefoot and Midfoot: A 12.5-Year Study at a University Hospital.Foot & ankle specialist · 2026Article
- Apposed ("Kissing") Diaphyseal Osteochondromas of Adjacent Metatarsals in a Non-syndromic Adult: A Case Report.Cureus · 2026Article
- A Soft Tissue Osteochondrolipoma of the Lateral Ankle: A Case Report and Clinical Insight.Case reports in orthopedics · 2026Article
- Retrospective clinicopathological analysis of 193 cases of bone and soft tissue tumors in the foot and ankle.Acta orthopaedica et traumatologica turcica · 2025Article
- The Giant Cell Tumor of 1st Metatarsal in a Young Adult: A Rare Versatile Management with Fibula Cortical Graft.Journal of orthopaedic case reports · 2025Article
- Tenosynovial giant cell tumours of the foot and ankle: a retrospective single centre experience with surgical treatment of 34 cases.BMC cancer · 2025Article
- 3D-Printed Talus-Calcaneus Prosthesis in Treating Ewing's Sarcoma: A Case Report.Orthopaedic surgery · 2025Article
- Principles of Defect Reconstruction After Wide Resection of Primary Malignant Bone Tumors of the Calcaneus: A Contemporary Review.Foot & ankle orthopaedics · 2024Review
- Insights into the Distribution Patterns of Foot and Ankle Tumours: Update on the Perspective of a University Tumour Institute.Journal of clinical medicine · 2024Article
- Imaging modalities for non-acute pathologies of the foot and ankle.Journal of clinical orthopaedics and trauma · 2024Article
- Treatment trends of benign bone lesions in a suburban New York healthcare system.Journal of family medicine and primary care · 2023Article
- Rare giant schwannoma of superficial peroneal nerve on the dorsum of foot.BMJ case reports · 2023Article
- Allogenic Cancellous Bone versus Injectable Bone Substitute for Endoscopic Treatment of Simple Bone Cyst and Intraosseous Lipoma of the Calcaneus and Is Intraosseous Lipoma a Developmental Stage of a Simple Bone Cyst?Journal of clinical medicine · 2023Article
- Article
- Diffuse Tenosynovial Giant Cell Tumor Encircling the First Metatarsal Bone Remodeling after Resection. A Case Report.Journal of orthopaedic case reports · 2023Article
- Malignant Bone and Soft Tissue Lesions of the Foot.Journal of clinical medicine · 2023Review
- Postoperative clinical and functional outcomes in patients with tumor and tumor-like lesion of foot and ankle.Journal of foot and ankle research · 2022Article
- Pathergy of a Medial Heel Schwannoma.Cureus · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBone and soft tissue masses of the foot and ankle are not particularly rare but true neoplasia has to be strictly differentiated from pseudotumorous lesions. Diagnosis is often delayed as diagnostic errors are more common than in other regions. Awareness for this localization of musculoskeletal tumors is not very high and neoplasia is often not considered. The purpose of this study is to provide detailed information on the incidence and distribution patterns of foot and ankle tumors of a university tumor institute and propose a simple definition to facilitate comparison of future investigations.
methodsAs part of a retrospective, single-centre study, the data of patients that were treated for foot and ankle tumors between June 1997 and December 2015 in a musculoskeletal tumor centre were analyzed regarding epidemiologic information, entity and localization. Included were all cases with a true tumor of the foot and ankle. Exclusion criteria were incomplete information on the patient or entity (e.g. histopathological diagnosis) and all pseudotumoral lesions.
resultsOut of 7487 musculoskeletal tumors, 413 cases (5,52%) of tumors of the foot and ankle in 409 patients were included (215 male and 198 female patients). The average age of the affected patients was 36 ± 18y (min.3y, max.92y). Two hundred sixty-six tumors involved the bone (64%), among them 231 (87%) benign and 35 (13%) malignant. There were 147 soft tissue tumors (36%), 104 (71%) were benign, 43 (29%) malignant. The most common benign osseous tumor lesions included simple bone cysts, enchondroma and osteochondroma. By far the most common malignant bone tumor was chondrosarcoma. Common benign soft tissue tumors included pigmented villo-nodular synovitis, superifcial fibromatosis and schwannoma whereas the most common malignant members were synovial sarcoma and myxofibrosarcoma. Regarding anatomical localization, the hindfoot was affected most often.
conclusionsKnowledge of incidence and distribution patterns of foot and ankle tumors will help to correctly assess unclear masses and initiate the right steps in further diagnostics and treatment. Unawareness can lead to delayed diagnosis and inadequate treatment with serious consequences for the affected patient.
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