Evidence map›Paper›PMID 30001272›Full record

ReviewExercise and sport sciences reviews2018

Modulation of Energy Expenditure by Estrogens and Exercise in Women.

Kathleen M Gavin, Wendy M Kohrt, Dwight J Klemm, Edward L Melanson

Open access · greenAbstract readReview
In one paragraph

Review in Exercise and sport sciences reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Cross-sectional analysis of gonadal hormone expression and relevant factors in female centenarians in Hainan, China.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022
    Article
  9. Ovariectomy Interferes with Proteomes of Brown Adipose Tissue in Rats.International journal of medical sciences · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Sex Differences in Adipose Tissue Function.Endocrinology and metabolism clinics of North America · 2020
    Review
  15. Article
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Kathleen M GavinDivision of Geriatric Medicine, School of Medicine, University of Colorado Anschutz Medical Campus.
Wendy M KohrtDivision of Geriatric Medicine, School of Medicine, University of Colorado Anschutz Medical Campus.
Dwight J KlemmEastern Colorado VA Geriatric Research, Education, and Clinical Center, Denver.
Edward L MelansonDivision of Geriatric Medicine, School of Medicine, University of Colorado Anschutz Medical Campus.
Geriatric Research Education and Clinical Center · USUniversity of Colorado Anschutz Medical Campus · USVA Eastern Colorado Health Care System · US

Funding

University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
Suppression of ERalpha in Hematopoietic Stem Cell-Derived Adipocytes Increases Adiposity via Kynurenine and the Aryl Hydrocarbon ReceptorU54AG062319 · NIA · UNIVERSITY OF COLORADO DENVER · PI Kerrie Moreau · 2018 to 2026
$13.5M
Sex Hormones Differentially Regulate Production of Distinct Adipocyte PopulationP50HD073063 · NICHD · UNIVERSITY OF COLORADO DENVER · PI KOHRT, WENDY M · 2012 to 2017
$5.7M
MODULATION OF VISCERAL FAT BY ESTROGENS AFTER MENOPAUSER01AG018198 · NIA · UNIVERSITY OF COLORADO DENVER · PI KOHRT, WENDY M · 2000 to 2011
$4.7M
A Novel Adipocyte Population Arises From Bone Marrow Progenitor CellsR01DK078966 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI KLEMM, DWIGHT J · 2008 to 2016
$2.6M
The impact of estrogen status on the biological function of brown adipose tissue in women measured using quantitative PET/CTR01DK112260 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI MELANSON, EDWARD L · 2016 to 2018
$1.8M
Integrin signaling promotes production of adipocytes from hematopoietic cellsR01DK109547 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI KLEMM, DWIGHT J · 2016 to 2019
$1.4M
Sex differences in adipogenic potential of adipose tissue myeloid cells in humansK01DK109053 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI GAVIN, KATHLEEN MARIE · 2016 to 2020
$724k
Measurement of Bone Marrow-derived Adipocytes in HumansF32AG046957 · NIA · UNIVERSITY OF COLORADO DENVER · PI GAVIN, KATHLEEN MARIE · 2014 to 2014
$56k
BLRD VA I01 BX005135NCATS NIH HHS UL1 TR001082NCATS NIH HHS UL1 TR002535NCI NIH HHS P30 CA046934NIA NIH HHS F32 AG046957NIA NIH HHS L30 AG051234NIA NIH HHS R01 AG018198NIA NIH HHS U54 AG062319NICHD NIH HHS P50 HD073063NIDDK NIH HHS K01 DK109053NIDDK NIH HHS P30 DK048520NIDDK NIH HHS R01 DK078966NIDDK NIH HHS R01 DK109547NIDDK NIH HHS R01 DK112260
6 · The paper itself

Abstract

Reducing estrogen in women results in decreases in energy expenditure, but the mechanism(s) remain largely unknown. We postulate that the loss of estrogens in women is associated with increased accumulation of bone marrow-derived adipocytes in white adipose tissue, decreased activity of brown adipose tissue, and reduced levels of physical activity. Regular exercise may counteract the effects of estrogen deficiency.

Indexed as

Energy MetabolismExerciseAdipocytesAdipose Tissue, BrownAdipose Tissue, WhiteAnimalsEstrogensFemaleHumansMenopauseEstrogens

Identifiers

PMID30001272
PMCPMC6138559
OpenAlexW2883356880

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.