Evidence map›Paper›PMID 30001231›Full record

ArticleThe Pediatric infectious disease journal2019

Rhinovirus Species in Children With Severe Bronchiolitis: Multicenter Cohort Studies in the United States and Finland.

Kohei Hasegawa, Tuomas Jartti, Yury A Bochkov, James E Gern, Jonathan M Mansbach, Pedro A Piedra, Laura Toivonen, Carlos A Camargo

Abstract readMulticenter Study
In one paragraph

Article in The Pediatric infectious disease journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Epidemiology and genotypic diversity of rhinovirus in school-age children with acute respiratory illnesses seeking medical care.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2025
    Article
  2. Article
  3. Genotypic Diversity of Childhood Rhinovirus Infections.Journal of the Pediatric Infectious Diseases Society · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Role of viruses in asthma.Seminars in immunopathology · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kohei HasegawaFrom the Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Tuomas JarttiDepartment of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland.
Yury A BochkovDepartments of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
James E GernDepartments of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Jonathan M MansbachDepartment of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Pedro A PiedraDepartments of Molecular Virology and Microbiology and Pediatrics, Baylor College of Medicine, Houston, Texas.
Laura ToivonenFrom the Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Carlos A CamargoFrom the Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Funding

Wisconsin Infant Study Cohort (WISC)U19AI104317 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern, CHRISTINE Marie SEROOGY · 2013 to 2026
$22.5M
Host genetics, early-life microbiome, and childhood asthma: MARC-43 BostonUH3OD023253 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CARLOS ARTURO CAMARGO · 2018 to 2026
$12.1M
Nasal microRNA during bronchiolitis and age 6y asthma phenotypes: MARC-35 cohortR01AI127507 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO, FREISHTAT, ROBERT J · 2017 to 2021
$8.0M
Host genetics, early-life microbiome, and childhood asthma: MARC-43 BostonUG3OD023253 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2016 to 2024
$6.8M
Prospective Cohort Study of Severe Bronchiolitis and Risk of Recurrent WheezingU01AI087881 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2011 to 2016
$6.2M
Infant specific-IgE, rhinovirus-C bronchiolitis, and incident asthma in MARC-35R01AI114552 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2015 to 2019
$4.2M
Viral persistence & the microbiome in bronchiolitis and risk of recurrent wheezeR01AI108588 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI MANSBACH, JONATHAN M · 2015 to 2018
$2.9M
Cytokines & transcriptomes in rhinovirus bronchiolitis and risk of incident asthmaR21HL129909 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HASEGAWA, KOHEI · 2015 to 2016
$506k
NHLBI NIH HHS R21 HL129909NIAID NIH HHS R01 AI108588NIAID NIH HHS R01 AI114552NIAID NIH HHS R01 AI127507NIAID NIH HHS U01 AI087881NIAID NIH HHS U19 AI104317NIH HHS UG3 OD023253NIH HHS UH3 OD023253
6 · The paper itself

Abstract

In this analysis of 2 prospective multicenter, multi-year cohorts of children hospitalized for bronchiolitis in the United States and Finland, 306 rhinovirus infections were genotyped. Rhinovirus-A and -C species were predominant in the US study, while rhinovirus-C species was predominant in the Finland study. In both cohorts, there were no significant between-species differences in clinical characteristics, including acute severity measures.

Indexed as

Bronchiolitis, ViralFemaleFinlandHospitalizationHumansInfantMaleMolecular TypingPicornaviridae InfectionsProspective StudiesRhinovirusSeverity of Illness IndexUnited States

Identifiers

PMID30001231
PMCPMC6329669

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.