Evidence map›Paper›PMID 30001217›Full record

ArticleAging2018

Hybrid complexes of high and low molecular weight hyaluronan delay in vitro replicative senescence of mesenchymal stromal cells: a pilot study for future therapeutic application.

Nicola Alessio, Antonietta Stellavato, Tiziana Squillaro, Stefania Del Gaudio, Giovanni Di Bernardo, Gianfranco Peluso, Mario De Rosa, Chiara Schiraldi, Umberto Galderisi

Open access · greenAbstract read
In one paragraph

Article in Aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
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  8. Article
  9. Adult Mesenchymal Stem Cells in Presence of Glycosaminoglycans.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  10. Article
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  14. [Paradigm shift in understanding hyaluronic acid filler effects].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2021
    Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Nicola AlessioDepartment of Experimental Medicine, Biotechnology and Molecular Biology Section, University of Campania "Luigi Vanvitelli", Naples, Italy.
Antonietta StellavatoDepartment of Experimental Medicine, Biotechnology and Molecular Biology Section, University of Campania "Luigi Vanvitelli", Naples, Italy.
Tiziana SquillaroDepartment of Experimental Medicine, Biotechnology and Molecular Biology Section, University of Campania "Luigi Vanvitelli", Naples, Italy.
Stefania Del GaudioDepartment of Experimental Medicine, Biotechnology and Molecular Biology Section, University of Campania "Luigi Vanvitelli", Naples, Italy.
Giovanni Di BernardoDepartment of Experimental Medicine, Biotechnology and Molecular Biology Section, University of Campania "Luigi Vanvitelli", Naples, Italy.
Gianfranco PelusoInstitute of Agri-Environmental Biology and Forestry (IBAF), CNR, Naples, Italy.
Mario De RosaDepartment of Experimental Medicine, Biotechnology and Molecular Biology Section, University of Campania "Luigi Vanvitelli", Naples, Italy.
Chiara SchiraldiDepartment of Experimental Medicine, Biotechnology and Molecular Biology Section, University of Campania "Luigi Vanvitelli", Naples, Italy.
Umberto GalderisiSbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Temple University, Philadelphia, PA 19107, USA.
University of Campania "Luigi Vanvitelli" · ITDeleted Institution

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells, a subpopulation of mesenchymal stromal cells (MSCs), are present in the stroma of several tissues. MSC

Indexed as

AdipocytesAdipogenesisbeta-GalactosidaseCell DifferentiationCell ProliferationCellular SenescenceChondrocytesChondrogenesisHumansHyaluronic AcidMesenchymal Stem CellsPilot Projectsbeta-GalactosidaseHyaluronic Acidextracellular matrixhyaluronanmesenchymal stromal cellssenescence

Identifiers

PMID30001217
PMCPMC6075440
OpenAlexW2854894982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.