ArticleWorld journal of surgical oncology2018
Are ADC values of readout-segmented echo-planar diffusion-weighted imaging (RESOLVE) correlated with pathological prognostic factors in rectal adenocarcinoma?
Article in World journal of surgical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Pretreatment Apparent Diffusion Coefficient Cannot Predict Histopathological Features and Response to Neoadjuvant Radiochemotherapy in Rectal Cancer: A Meta-Analysis.Digestive diseases (Basel, Switzerland) · 2022Pooled it
- Comparison of reduced FOV diffusion-weighted imaging of rectal cancer at 5.0T ultra-high field versus 3.0T MRI: image quality and histopathological T staging.BMC medical imaging · 2025Article
- Assessment of prognostic indicators and KRAS mutations in rectal cancer using a fractional-order calculus MR diffusion model: whole tumor histogram analysis.Abdominal radiology (New York) · 2025Article
- Assessment of the imaging quality and heterogeneous predictive value of readout-segmented echo planar imaging for diffusion-weighted rectal MRI.Frontiers in oncology · 2025Article
- Value of perfusion parameters from golden-angle radial sparse parallel dynamic contrast-enhanced magnetic resonance imaging in predicting pathological complete response after neoadjuvant chemoradiotherapy for locally advanced rectal cancerDiagnostic and interventional radiology (Ankara, Turkey) · 2024Article
- Article
- Application value of simultaneous multislice readout-segmented echo-planar imaging for diffusion-weighted MRI in differentiation of rectal cancer grade.Magma (New York, N.Y.) · 2023Article
- Golden-angle radial sparse parallel magnetic resonance imaging of rectal perfusion: utility in the diagnosis of poorly differentiated rectal cancer.Quantitative imaging in medicine and surgery · 2023Article
- High-resolution integrated dynamic shimming diffusion-weighted imaging (DWI) in the assessment of rectal cancer.European radiology · 2023Article
- Feasibility of high-resolution readout-segmented echo-planar imaging with simultaneous multislice imaging in assessing rectal cancer.Abdominal radiology (New York) · 2023Article
- Article
- Article
- High resolution diffusion-weighted imaging with readout segmentation of long variable echo-trains for determining myometrial invasion in endometrial carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2020Article
- MRI-based radiomics of rectal cancer: preoperative assessment of the pathological features.BMC medical imaging · 2019Article
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8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDiffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) values as imaging biomarkers of rectal cancer are currently a hot research spot. The use of ADC values for preoperative judgment of pathological features in rectal cancer has been generally accepted. The image quality evaluation of conventional diffusion is severe deformation, and the measurement of ADC values can easily lead to bias. Readout-segmented echo-planar diffusion-weighted imaging (RESOLVE) provides high signal-to-noise ratio images and significantly reduces distortions caused by magnetosensitive effects. The purpose of this study was to explore the correlations between ADC values of RESOLVE and pathological prognostic factors in rectal adenocarcinoma.
methodsWe collected pathological data of 89 patients with pathologically confirmed rectal adenocarcinoma who directly underwent surgical resection without receiving adjuvant therapy. The patients were grouped according to the pathologic type, gross classification, degree of differentiation, TN stage, and immunohistochemical expression of epidermal growth factor receptor (EGFR).
resultsRESOLVE ADC values of rectal cancer were measured at b = 800, and correlations between the RESOLVE ADC values obtained in different groups were analysed. We found that RESOLVE ADC values in the ulcer-type group were significantly higher than those in the eminence-type group.
conclusionRESOLVE ADC values in different pathologic types of rectal cancer were significantly different. RESOLVE ADC values in the EGFR-positive group were significantly lower than those in the EGFR-negative group. There was no significant difference in RESOLVE ADC values between different degrees of pathologic differentiation, TN stages, and positive or negative lymph nodes. The quantitative description of RESOLVE ADC values could be used to assess the biological behaviour of rectal adenocarcinoma.
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