Evidence map›Paper›PMID 30001174›Full record

ArticleVirulence2018

IgM cleavage by Streptococcus suis reduces IgM bound to the bacterial surface and is a novel complement evasion mechanism.

Viktoria Rungelrath, Christine Weiße, Nicole Schütze, Uwe Müller, Marita Meurer, Manfred Rohde, Jana Seele, Peter Valentin-Weigand, Michael Kirschfink, Andreas Beineke and 3 more

Open access · goldAbstract read
In one paragraph

Article in Virulence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Review
  3. AVeterinary sciences · 2026
    Article
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  7. Article
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  11. Article
  12. Article
  13. Review
  14. Review
  15. Immunoglobulin M-degrading enzyme ofFrontiers in immunology · 2023
    Article
  16. d-Alanylation of Lipoteichoic Acids inFrontiers in microbiology · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Viktoria Rungelratha Institute for Bacteriology and Mycology, Centre for Infectious Diseases, Veterinary Faculty , University of Leipzig , Leipzig , Germany.
Christine Weißea Institute for Bacteriology and Mycology, Centre for Infectious Diseases, Veterinary Faculty , University of Leipzig , Leipzig , Germany.
Nicole Schützeb Institute of Immunology, Centre for Infectious Diseases, Veterinary Faculty , University of Leipzig , Leipzig , Germany.
Uwe Müllerb Institute of Immunology, Centre for Infectious Diseases, Veterinary Faculty , University of Leipzig , Leipzig , Germany.
Marita Meurerc Department of Physiological Chemistry and Research Center for Emerging Infections and Zoonoses (RIZ) , University of Veterinary Medicine Hannover , Hannover , Germany.
Manfred Rohded Central Facility for Microscopy , Helmholtz Centre for Infection Research , Braunschweig , Germany.
Jana Seelee Department of Neuropathology , University Medical Center Göttingen, Georg-August-University Göttingen , Göttingen , Germany.ORCID 0000-0002-2452-965X
Peter Valentin-Weigandg Institute for Microbiology, Centre for Infection Medicine , University of Veterinary Medicine Hannover , Hanover , Germany.
Michael Kirschfinkh Institute of Immunology , University of Heidelberg , Heidelberg , Germany.
Andreas Beinekei Department of Pathology , University of Veterinary Medicine Hannover , Hannover , Germany.
Wieland Schrödla Institute for Bacteriology and Mycology, Centre for Infectious Diseases, Veterinary Faculty , University of Leipzig , Leipzig , Germany.
René Bergmanna Institute for Bacteriology and Mycology, Centre for Infectious Diseases, Veterinary Faculty , University of Leipzig , Leipzig , Germany.
Christoph Georg Baumsa Institute for Bacteriology and Mycology, Centre for Infectious Diseases, Veterinary Faculty , University of Leipzig , Leipzig , Germany.ORCID 0000-0001-9149-1615
Leipzig University · DEUniversity of Veterinary Medicine Hannover, Foundation · DEHeidelberg University · DEHelmholtz Centre for Infection Research · DEUniversitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Streptococcus suis (S. suis) causes meningitis, arthritis and endocarditis in piglets. The aim of this study was to characterize the IgM degrading enzyme of S. suis (Ide

Indexed as

Immune EvasionAnimalsBacterial ProteinsBinding Sites, AntibodyComplement System ProteinsCysteine ProteasesHost-Pathogen InteractionsImmunoglobulin MMeningitisMutagenesisProteolysisSerogroupStreptococcal InfectionsStreptococcus suisSwineSwine DiseasesBacterial ProteinsComplement System ProteinsCysteine ProteasesImmunoglobulin Mcysteine proteaseIdeS-family proteaseIdeSsuisIgMopsonizationStreptococcus suis

Identifiers

PMID30001174
PMCPMC6177247
OpenAlexW2884077362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.