Evidence map›Paper›PMID 29999581›Full record

ArticleMicrocirculation (New York, N.Y. : 1994)2018

Ovarian hormones modulate endothelin-1 receptor responses in young women.

Kelly N Sebzda, Andrew V Kuczmarski, Ryan T Pohlig, Shannon L Lennon, David G Edwards, Megan M Wenner

Open access · greenAbstract read
In one paragraph

Article in Microcirculation (New York, N.Y. : 1994), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Trial
  3. ETAmerican journal of physiology. Heart and circulatory physiology · 2021
    Trial
  4. Review
  5. Review
  6. Article
  7. Sodium intake and biological sex influence urinary endothelin-1 in salt-resistant adults: a pilot study.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  8. Article
  9. Endothelial dysfunction in middle-aged and older men with low testosterone is associated with elevated circulating endothelin-1.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kelly N SebzdaDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.
Andrew V KuczmarskiDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.
Ryan T PohligBiostatistic Core Facility, College of Health Sciences, University of Delaware, Newark, Delaware.
Shannon L LennonDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.
David G EdwardsDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.
Megan M WennerDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.ORCID 0000-0003-0055-783X
University of Delaware · US

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI MELINDA K DUNCAN · 2012 to 2026
$67.2M
Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Gregory E Hicks · 2013 to 2026
$60.5M
Vascular Consequences of Duchenne Muscular DystrophyP20GM113125 · NIGMS · UNIVERSITY OF DELAWARE · PI LENNON, SHANNON L. · 2016 to 2025
$23.3M
NIGMS NIH HHS P20 GM103446NIGMS NIH HHS P20 GM113125NIGMS NIH HHS U54 GM104941
6 · The paper itself

Abstract

objectiveWe recently demonstrated ETB

methodsWe measured cutaneous vasodilatory responses in 12 young women (22 ± 1 years, 23 ± 1 kg/m

resultsSerum estradiol (ML: 118 ± 16 vs EF: 44 ± 9 pg/mL, P < 0.05) and progesterone (ML: 8.3 ± 1.0 vs EF: 0.7 ± 0.2 ng/mL, P < 0.05) were higher during ML vs EF phase. ETB

conclusionsThese data suggest that fluctuations in ovarian hormones modulate ETB

Indexed as

EstradiolFemaleHormonesHumansOvaryProgesteroneReceptor, Endothelin AReceptor, Endothelin BSkinVasodilationYoung AdultEstradiolHormonesProgesteroneReceptor, Endothelin AReceptor, Endothelin Bcutaneous microdialysisendothelin-B receptorsex hormones

Identifiers

PMID29999581
PMCPMC7577781
OpenAlexW2234505127

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.