Evidence map›Paper›PMID 29999569›Full record

ArticleHuman brain mapping2018

Clinical characteristics of cognitive impairment in patients with Parkinson's disease and its related pattern in

Lei Wu, Feng-Tao Liu, Jing-Jie Ge, Jue Zhao, Yi-Lin Tang, Wen-Bo Yu, Huan Yu, Tim Anderson, Chuan-Tao Zuo, Ling Chen and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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  14. Independent effect of neurogenic orthostatic hypotension on mild cognitive impairment in Parkinson's disease.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Lei WuDepartment of Neurology & National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Feng-Tao LiuDepartment of Neurology & National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Jing-Jie GePET Center, Huashan Hospital, Fudan University, Shanghai, China.
Jue ZhaoDepartment of Neurology & National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Yi-Lin TangDepartment of Neurology & National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Wen-Bo YuDepartment of Neurology & National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Huan YuDepartment of Neurology & National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Tim AndersonDepartment of Medicine, University of Otago, New Zealand Brain Research Institute, and Brain Research New Zealand, Christchurch, New Zealand.
Chuan-Tao ZuoPET Center, Huashan Hospital, Fudan University, Shanghai, China.
Ling ChenDepartment of Neurology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jian WangDepartment of Neurology & National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0001-9952-0898
Fudan University · CNSun Yat-sen University · CNNew Zealand Brain Research Institute · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to characterize the clinical features and the related cerebral glucose metabolism pattern of cognitive impairments in Parkinson's disease (PD) with positron emission tomography (PET) imaging. We recruited 168 PD patients and 100 age-matched healthy controls of similar education and gender distribution. All of those enrolled underwent clinical assessment including the unified Parkinson's disease rating scale motor score, Hoehn and Yahr scale, and comprehensive neuropsychological tests including domains of executive function, attention, memory, visuospatial function, and language. Demographics and the results of cognitive measures were compared between patients and healthy controls. Cognition status was classified as PD patients with dementia (PD-D), PD patients with mild cognitive impairment (PD-MCI), or PD patients with normal cognition (PD-NC). In 53 PD patients who underwent

Indexed as

Cognitive DysfunctionDementiaParkinson DiseaseAdultAgedAged, 80 and overAttentionExecutive FunctionFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedPositron-Emission TomographyFluorodeoxyglucose F1818F-FDG PETcognitive impairmentneuropsychologyParkinson's disease

Identifiers

PMID29999569
PMCPMC6866526
OpenAlexW2879894516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.