Evidence map›Paper›PMID 29998744›Full record

ArticleCartilage2020

Nondestructive Assessment of Articular Cartilage Electromechanical Properties after Osteochondral Autologous and Allogeneic Transplantation in a Goat Model.

Tomas Mickevicius, Alius Pockevicius, Audrius Kucinskas, Rimtautas Gudas, Justinas Maciulaitis, Arvydas Usas

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cartilage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tomas MickeviciusDepartment of Orthopaedics and Traumatology, Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Kaunas, Lithuania.
Alius PockeviciusPathology Center, Department of Veterinary Pathobiology, Veterinary Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Audrius KucinskasBiological Research Center Lithuanian University of Health Sciences, Kaunas, Lithuania.
Rimtautas GudasDepartment of Orthopaedics and Traumatology, Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Kaunas, Lithuania.
Justinas MaciulaitisDepartment of Orthopaedics and Traumatology, Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Kaunas, Lithuania.
Arvydas UsasInstitute of Physiology and Pharmacology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Hospital of Lithuanian University of Health Sciences Kaunas Clinics · LTLithuanian University of Health Sciences · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the applicability of a minimally invasive diagnostic device to evaluate the quality of articular cartilage following autologous (OAT) and allogeneic (OCA) osteochondral graft transplantation in goat model.

designOAT grafts were harvested from lateral femoral condyles (LFCs) and transplanted into osteochondral defects created in medial femoral condyles (MFCs) of contralateral knees. OCA grafts were transplanted into MFC condyles after

resultsTransplanted cartilage deteriorated within 6 months in all groups. Cartilage quality was better retained in OAT group compared with a decline in OCA group. QP and OAS scores were comparable in OAT and OCA groups at 3 months, but superior in OAT group at 6 months, according to all the methods applied. PRP injections significantly improved QP and OAS score at 6 months compared with 3 months in OAT group. QP moderately correlated with OAS, O'Driscoll score, and safranin O staining intensity.

conclusionsGrafts did not retain preoperative quality parameters at 6 months follow-up; however, OAT were superior to OCA grafts. PRP may have a beneficial effect on macroscopic and electromechanical properties of cartilage; however, histological improvement is yet to be proved. Electromechanical diagnostic device enables reliable assessment of transplanted cartilage.

Indexed as

AllograftsAnimalsArthroscopyAutograftsBone TransplantationCartilage, ArticularDisease Models, AnimalFemoral FracturesFemurGoatsIntra-Articular FracturesKnee JointMechanical PhenomenaMechanical TestsPlatelet-Rich PlasmaTransplantation, Autologousallograftautograftcartilage electromechanical propertiesosteochondral transplantationplatelet-rich plasma

Identifiers

PMID29998744
PMCPMC7298600
OpenAlexW2868222150

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.