Evidence map›Paper›PMID 29998397›Full record

ArticleMolecular neurobiology2019

Epigenetic Control of the Notch and Eph Signaling Pathways by the Prion Protein: Implications for Prion Diseases.

Théo Z Hirsch, Séverine Martin-Lannerée, Fabienne Reine, Julia Hernandez-Rapp, Laetitia Herzog, Michel Dron, Nicolas Privat, Bruno Passet, Sophie Halliez, Ana Villa-Diaz and 8 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 3 countries.

Théo Z HirschINSERM UMR 1124, 75006, Paris, France.
Séverine Martin-LanneréeINSERM UMR 1124, 75006, Paris, France.
Fabienne ReineINRA, Université Paris-Saclay, UR 892 Virologie Immunologie Moléculaires, 78350, Jouy-en-Josas, France.
Julia Hernandez-RappINSERM UMR 1124, 75006, Paris, France.
Laetitia HerzogINRA, Université Paris-Saclay, UR 892 Virologie Immunologie Moléculaires, 78350, Jouy-en-Josas, France.
Michel DronINRA, Université Paris-Saclay, UR 892 Virologie Immunologie Moléculaires, 78350, Jouy-en-Josas, France.
Nicolas PrivatINSERM UMR 1127, CNRS UMR 7225, 75013, Paris, France.
Bruno PassetINRA UMR1313, Génétique Animale et Biologie Intégrative, 78350, Jouy-en-Josas, France.
Sophie HalliezINRA, Université Paris-Saclay, UR 892 Virologie Immunologie Moléculaires, 78350, Jouy-en-Josas, France.
Ana Villa-DiazCentro de Investigación en Sanidad Animal-INIA, 28130, Madrid, Spain.
Caroline LacrouxINRA-ENVT UMR 1225, 31076, Toulouse, France.
Victor KleinINSERM UMR 1124, 75006, Paris, France.
Stéphane HaïkINSERM UMR 1127, CNRS UMR 7225, 75013, Paris, France.
Olivier AndréolettiINRA-ENVT UMR 1225, 31076, Toulouse, France.
Juan-Maria TorresCentro de Investigación en Sanidad Animal-INIA, 28130, Madrid, Spain.
Jean-Luc VilotteINRA UMR1313, Génétique Animale et Biologie Intégrative, 78350, Jouy-en-Josas, France.
Vincent BéringueINSERM UMR 1127, CNRS UMR 7225, 75013, Paris, France.
Sophie Mouillet-RichardINSERM UMR 1124, 75006, Paris, France. sophie.mouillet-richard@parisdescartes.fr.ORCID http://orcid.org/0000-0002-8950-1949
Délégation Paris 5 · FRCentre National de la Recherche Scientifique · FRUniversité Paris-Saclay · FRAgroParisTech · FRCentro de Investigación en Sanidad AnimalÉcole Nationale Vétérinaire de Toulouse · FRInserm · FR

Funding

Fondation pour la Recherche Médicale DEQ20150331689
6 · The paper itself

Abstract

Among the ever-growing number of self-replicating proteins involved in neurodegenerative diseases, the prion protein PrP remains the most infamous for its central role in transmissible spongiform encephalopathies (TSEs). In these diseases, pathogenic prions propagate through a seeding mechanism, where normal PrP

Indexed as

AnimalsEpigenesis, GeneticMiceNeuronsPrion DiseasesPrion ProteinsReceptors, Eph FamilyReceptors, NotchSignal TransductionPrion ProteinsReceptors, Eph FamilyReceptors, NotchCellular prion proteinEphHDACNotchPrion infection

Identifiers

PMID29998397
OpenAlexW2880494313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.