ReviewEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2018
Prognosis of septic cavernous sinus thrombosis remarkably improved: a case series of 12 patients and literature review.
Review in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Refractory cavernous sinus thrombophlebitis complicated by brain abscess and infectious hydrocephalus: a case report and literature review.BMC infectious diseases · 2026Review
- Article
- Article
- Anticoagulation in the management of septic cavernous sinus thrombosis secondary to rhino-orbito-cerebral mucormycosis: A retrospective real-world experience.Current journal of neurology · 2024Article
- Serious Complications and Treatment Strategies Associated with Odontogenic Infections.The Eurasian journal of medicine · 2023Article
- Concomitant cavernous sinus thrombosis and central serous chorioretinopathy in a patient with total ophthalmoplegia and monocular blindness: a case report.Annals of medicine and surgery (2012) · 2023Article
- Article
- Review
- Infectious Cavernous Sinus Thrombosis Presenting as Temporal Arteritis-A Case Report.The Neurohospitalist · 2021Article
- Cavernous sinus thrombosis: a late complication of head and neck surgery.BMJ case reports · 2021Article
- Septic cavernous sinus thrombosis secondary to halo vest pin site infection.North American Spine Society journal · 2020Article
- Cavernous sinus thrombosis caused byAmerican journal of ophthalmology case reports · 2020Article
- Article
- Bilateral cavernous sinus and left dural sigmoid sinus thrombosis associated with extreme exertion: a case report.Arquivos brasileiros de oftalmologiaArticle
- Successful management of cavernous sinus thrombosis without anticoagulation: a neuro-ophthalmologic case report.Frontiers in neurologyArticle
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSeptic cavernous sinus thrombosis (CST) is a rare complication of infections in the head and neck area. CST is notorious for its bad prognosis, with high mortality and morbidity rates described in literature. However, these rates are based on old series. We question whether the prognosis of CST is currently still as devastating. The primary purpose of this study is to assess the mortality and morbidity of CST.
methodsUsing the databases of all relevant specialties in our tertiary referral hospital, we collected all the patients treated for CST in the period 2005-2017. In addition, a PubMed search, using the mesh term 'cavernous sinus thrombosis', was performed.
resultsWe found 12 patients with CST in the study period. Of the 12 patients, 11 survived and 9 recovered without any permanent deficits. Seven patients were treated with anticoagulation, and in none of the patients we saw hemorrhagic complications. In literature, older articles describe higher mortality rates (14-80%), but more recent articles report mortality and morbidity rates similar to our results.
conclusionsThe prognosis of CST nowadays is more favorable than previously described. Anticoagulation seems to be a safe addition to antibiotic and surgical treatment, at least in patients without central nervous system infection.
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