Evidence map›Paper›PMID 29998225›Full record

ArticleJournal of childhood obesity2018

Salivary Cortisol Does Not Correlate with Metabolic Syndrome Markers or Subjective Stress in Overweight Children.

Robert B Strait, Marcia J Slattery, Aaron L Carrel, Jens Eickhoff, David B Allen

Open access · diamondAbstract read
In one paragraph

Article in Journal of childhood obesity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Pediatric obesity · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Robert B StraitDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, H4-436, Madison WI, 53792.
Marcia J SlatteryDepartment of Child and Adolescent Psychiatry, University of Wisconsin School of Medicine and Public Health, 6001 Research Park Blvd, Madison, WI 53719.
Aaron L CarrelDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, H4-436, Madison WI, 53792.
Jens EickhoffDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, H4-436, Madison WI, 53792.
David B AllenDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, H4-436, Madison WI, 53792.
University of Wisconsin–Madison · US

Funding

BIOMEDICAL ALCOHOL RESEARCH TRAINING PROGRAMT32AA007577 · NIAAA · LSU HEALTH SCIENCES CENTER · PI PATRICIA E. MOLINA · 1999 to 2026
$9.6M
Childhood Diabetes Clinical & Molecular Research Training ProgramT32DK077586 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI Brigid Ellen Gregg, Scott B. Reeder · 2008 to 2026
$2.4M
NIAAA NIH HHS T32 AA007577NIDDK NIH HHS T32 DK077586
6 · The paper itself

Abstract

objectiveBeing overweight is a risk factor for metabolic syndrome in children, but not all overweight children develop metabolic syndrome. Cortisol excess from chronic psychological stress has been proposed as an independent risk factor for metabolic syndrome in this already at-risk population. The present study assesses the relationship of biochemical and body composition radiographic markers of metabolic syndrome to salivary cortisol and self-report of chronic psychological stress in a cohort of overweight children.

methodsThis cross-sectional study took place in a multi-disciplinary pediatric obesity clinic at a tertiary care hospital, and involved fifteen children with BMI at or above the 85

resultsIn this pilot study, no correlation was found between salivary cortisol measures and questionnaire scores of subjective stress or bullying, and no correlation was found between any of these measures and markers of metabolic syndrome (dyslipidemia, insulin resistance, increased abdominal fat).

conclusionsThese results suggest that measures of psychological stress, whether biochemical or subjective, do not appear to predict risk of metabolic syndrome in overweight children. While ease of collection and demonstrated utility both in detection of pediatric Cushing disease and in adult psychological research make salivary cortisol assessment an attractive clinical tool, further investigation into the value of salivary measures in pediatric stress research is needed.

Indexed as

CAR (Cortisol Awakening Response)Chronic HypercortisolemiaMetabolic SyndromePsychological StressSalivary Cortisol

Identifiers

PMID29998225
PMCPMC6037313
OpenAlexW2801262968

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.