Evidence map›Paper›PMID 29998196›Full record

ArticleHeliyon2018

Transgenic overexpression of the SUR2A-55 splice variant in mouse heart reduces infract size and promotes protective mitochondrial function.

Mohun Ramratnam, Barrett Kenny, John W Kyle, Brandi Wiedmeyer, Timothy A Hacker, David Y Barefield, Elizabeth M McNally, Jonathan C Makielski

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Female cardioprotection in ischemia/reperfusion: Isn't a SUR thing anymore?Journal of molecular and cellular cardiology plus · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Genetic Discovery of ATP-Sensitive KCirculation. Arrhythmia and electrophysiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mohun RamratnamDivision of Cardiovascular Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
Barrett KennyDivision of Cardiovascular Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
John W KyleDivision of Cardiovascular Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
Brandi WiedmeyerDivision of Cardiovascular Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
Timothy A HackerCardiovascular Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
David Y BarefieldCenter for Genetic Medicine, Northwestern University, Chicago, IL, United States.
Elizabeth M McNallyCenter for Genetic Medicine, Northwestern University, Chicago, IL, United States.
Jonathan C MakielskiDivision of Cardiovascular Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States.
University of Wisconsin–Madison · USNorthwestern University · US

Funding

Mechanisms of sulfonylurea receptor mediated cardiomyopathyR01HL122109 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MAKIELSKI, JONATHAN C, MCNALLY, ELIZABETH M · 2015 to 2018
$2.4M
Myosin binding protein H-like and its role in cardiomyopathyF32HL131304 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BAREFIELD, DAVID Y · 2016 to 2018
$155k
NHLBI NIH HHS F32 HL131304NHLBI NIH HHS R01 HL122109
6 · The paper itself

Abstract

ATP-sensitive potassium channels found in both the sarcolemma (sarcK

Indexed as

CardiologyMedicinePhysiology

Identifiers

PMID29998196
PMCPMC6037880
OpenAlexW2810603661

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.