Evidence map›Paper›PMID 29998149›Full record

ArticleAsia Oceania journal of nuclear medicine & biology2018

The Value of Technetium-99m Labeled Alpha-Melanocyte-Stimulating Hormone (

Saeed Farzanefar, Rahman Etemadi, Mohammad Shirkhoda, Habibollah Mahmoodzadeh, Mostafa Erfani, Babak Fallahi, Mehrshad Abbasi, Narjess Ayati, Arman Hassanzadeh-Rad, Mohammad Eftekhari and 1 more

Open access · greenAbstract read
In one paragraph

Article in Asia Oceania journal of nuclear medicine & biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Current medicinal chemistry · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Saeed FarzanefarDepartment of Nuclear Medicine, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Rahman EtemadiResearch Center for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad ShirkhodaDepartment of General Surgery, Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Habibollah MahmoodzadehDepartment of General Surgery, Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mostafa ErfaniRadiation Application Research School, Nuclear Science and Technology Research Institute, Tehran, Iran.
Babak FallahiResearch Center for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mehrshad AbbasiDepartment of Nuclear Medicine, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Narjess AyatiNuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Arman Hassanzadeh-RadResearch Center for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad EftekhariResearch Center for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Davood BeikiResearch Center for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRShariati Hospital · IRMashhad University of Medical Sciences · IRNuclear Science and Technology Research Institute

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMalignant melanoma is the most lethal type of skin cancers with unfavorable prognosis. Alpha-MSH peptide analogues have a high affinity for melanocortine-1 (MC1) receptors on melanocytes over expressing in malignant melanoma cells. Pre-clinical studies have shown promising results for radiolabeled MSH imaging in this malignancy. The purpose of this study is to assess the diagnostic value of

methodsTwenty-one patients (13 men) with pathologically confirmed malignant melanoma with or without metastatic distribution were included in this study. 740-1110 MBq

resultsThe T/BG ratio for the primary tumor bed was 2.51±2.26, 2.56±2.48 and 1.92±1.79 minutes in the whole body scans 20, 120 and 240 minutes post injection, respectively. The sensitivity, specificity, negative and positive predictive values were 75%, 80%, 50% and 92% for primary lesion and 25%, 100%, 68% and 100% for distant metastasis, respectively.

conclusion

Indexed as

99mTc-α-MSHMalignant MelanomaMelanocortine-1 receptorMelanocyte stimulating hormoneRadiolabeled peptide

Identifiers

PMID29998149
PMCPMC6038966
OpenAlexW2886253426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.