Evidence map›Paper›PMID 29997909›Full record

ArticleEuropean journal of microbiology & immunology2018

Anti-inflammatory Effects of the Octapeptide NAP in Human Microbiota-Associated Mice Suffering from Subacute Ileitis.

Ulrike Escher, Eliezer Giladi, Ildikò R Dunay, Stefan Bereswill, Illana Gozes, Markus M Heimesaat

Open access · diamondAbstract read
In one paragraph

Article in European journal of microbiology & immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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  11. Multidrug-ResistantFrontiers in immunology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Ulrike EscherCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Microbiology and Infection Immunology, Berlin, Germany.
Eliezer GiladiDepartment of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Aviv University, Aviv, Israel.
Ildikò R DunayInstitute of Inflammation and Neurodegeneration, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Stefan BereswillCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Microbiology and Infection Immunology, Berlin, Germany.
Illana GozesDepartment of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Aviv University, Aviv, Israel.
Markus M HeimesaatCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Microbiology and Infection Immunology, Berlin, Germany.
Tel Aviv University · ILCharité - Universitätsmedizin Berlin · DEFreie Universität Berlin · DEHumboldt-Universität zu Berlin · DEOtto-von-Guericke University Magdeburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The octapeptide NAP is well known for its neuroprotective properties. We here investigated whether NAP treatment could alleviate pro-inflammatory immune responses during experimental subacute ileitis. To address this, mice with a human gut microbiota were perorally infected with one cyst of

Indexed as

activity-dependent neuroprotective protein (ADNP)extra-intestinal and systemic immune responsesfecal microbiota transplantationhost immunityhost-pathogen interactionshuman gut microbiotaintestinaloctapeptide NAPsecondary abiotic (gnotobiotic) micesubacute ileitisToxoplasma gondii

Identifiers

PMID29997909
PMCPMC6038539
OpenAlexW2803770232

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.