Evidence map›Paper›PMID 29997826›Full record

ArticleChemical science2016

Optical control of neuronal firing

Yuta Takano, Tomohiro Numata, Kazuto Fujishima, Kazuaki Miyake, Kazuya Nakao, Wesley David Grove, Ryuji Inoue, Mineko Kengaku, Shigeyoshi Sakaki, Yasuo Mori and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Yuta TakanoInstitute for Integrated Cell-Material Sciences (WPI-iCeMS) , Kyoto University , Sakyo-ku , Kyoto 606-8501 , Japan . Email: kengaku@icems.kyoto-u.ac.jp.
Tomohiro NumataDepartment of Physiology , Graduate School of Medical Sciences , Fukuoka University , Nanakuma 7-45-1, Johnan-ku , Fukuoka 814-0180 , Japan.
Kazuto FujishimaInstitute for Integrated Cell-Material Sciences (WPI-iCeMS) , Kyoto University , Sakyo-ku , Kyoto 606-8501 , Japan . Email: kengaku@icems.kyoto-u.ac.jp.
Kazuaki MiyakeDepartment of Molecular Engineering , Graduate School of Engineering , Kyoto University , Nishikyo-ku , Kyoto 615-8510 , Japan . Email: imahori@scl.kyoto-u.ac.jp.
Kazuya NakaoDepartment of Molecular Engineering , Graduate School of Engineering , Kyoto University , Nishikyo-ku , Kyoto 615-8510 , Japan . Email: imahori@scl.kyoto-u.ac.jp.
Wesley David GroveInstitute for Integrated Cell-Material Sciences (WPI-iCeMS) , Kyoto University , Sakyo-ku , Kyoto 606-8501 , Japan . Email: kengaku@icems.kyoto-u.ac.jp.
Ryuji InoueDepartment of Physiology , Graduate School of Medical Sciences , Fukuoka University , Nanakuma 7-45-1, Johnan-ku , Fukuoka 814-0180 , Japan.
Mineko KengakuInstitute for Integrated Cell-Material Sciences (WPI-iCeMS) , Kyoto University , Sakyo-ku , Kyoto 606-8501 , Japan . Email: kengaku@icems.kyoto-u.ac.jp.
Shigeyoshi SakakiFukui Institute for Fundamental Chemistry , Kyoto University , Sakyo-ku , Kyoto 606-8103 , Japan.
Yasuo MoriDepartment of Synthetic Chemistry and Biological Chemistry , Graduate School of Engineering , Kyoto University , Nishikyo-ku , Kyoto 615-8510 , Japan . Email: mori@sbchem.kyoto-u.ac.jp.
Tatsuya MurakamiInstitute for Integrated Cell-Material Sciences (WPI-iCeMS) , Kyoto University , Sakyo-ku , Kyoto 606-8501 , Japan . Email: kengaku@icems.kyoto-u.ac.jp.
Hiroshi ImahoriInstitute for Integrated Cell-Material Sciences (WPI-iCeMS) , Kyoto University , Sakyo-ku , Kyoto 606-8501 , Japan . Email: kengaku@icems.kyoto-u.ac.jp.ORCID 0000-0003-3506-5608
Kyoto University · JPFukuoka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of porphyrin-fullerene linked molecules has been synthesized to evaluate the effects of substituents and molecular structures on their charge-separation yield and the lifetime of a final charge-separated state in various hydrophilic environments. The selected high-performance molecule effectively achieved depolarization in a plasma cell membrane by visible light as well as two-photon excitation using a near-infrared light laser. Moreover, it was revealed that the depolarization can trigger neuronal firing in rat hippocampal neurons, demonstrating the potential and versatility for controlling cell functions using light.

Identifiers

PMID29997826
PMCPMC6006863
OpenAlexW2279460912

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.