Evidence map›Paper›PMID 29997801›Full record

ArticleChemical science2016

Rational design of supramolecular hemin/G-quadruplex-dopamine aptamer nucleoapzyme systems with superior catalytic performance.

H Bauke Albada, Eyal Golub, Itamar Willner

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 85 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Construction and Application of DNAzyme-based Nanodevices.Chemical research in Chinese universities · 2023
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Polymer tube nanoreactors via DNA-origami templated synthesis.Chemical communications (Cambridge, England) · 2018
    Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

H Bauke AlbadaInstitute of Chemistry , The Minerva Center for Biohybrid Complex Systems , The Hebrew University of Jerusalem , Jerusalem , 91904 , Israel . Email: willnea@vms.huji.ac.il ; ; Tel: +972-2-6585272.ORCID 0000-0003-3659-2434
Eyal GolubInstitute of Chemistry , The Minerva Center for Biohybrid Complex Systems , The Hebrew University of Jerusalem , Jerusalem , 91904 , Israel . Email: willnea@vms.huji.ac.il ; ; Tel: +972-2-6585272.
Itamar WillnerInstitute of Chemistry , The Minerva Center for Biohybrid Complex Systems , The Hebrew University of Jerusalem , Jerusalem , 91904 , Israel . Email: willnea@vms.huji.ac.il ; ; Tel: +972-2-6585272.
Hebrew University of Jerusalem · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rational design of a set of hemin/G-quadruplex (hGQ)-dopamine binding aptamer (DBA) conjugates, acting as nucleoapzymes, is described. The nucleoapzyme constructs consist of a hGQ DNAzyme as a catalytic unit and DBA as a substrate binding unit that are brought into spatial proximity by a duplex scaffold composed of complementary oligonucleotide strands. When the hGQ unit is linked to the duplex scaffold

Identifiers

PMID29997801
PMCPMC6005209
OpenAlexW2258113301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.