Evidence map›Paper›PMID 29997791›Full record

ArticleChemical science2016

A pillar[5]arene-based [2]rotaxane lights up mitochondria.

Guocan Yu, Dan Wu, Yang Li, Zhihua Zhang, Li Shao, Jiong Zhou, Qinglian Hu, Guping Tang, Feihe Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Pillararenes as Promising Carriers for Drug Delivery.International journal of molecular sciences · 2023
    Review
  8. Review
  9. Review
  10. Self-Assembly of Stimuli-Responsive [2]Rotaxanes by Amidinium Exchange.Journal of the American Chemical Society · 2021
    Article
  11. Review
  12. Article
  13. Article
  14. Tumor microenvironment responsive drug delivery systems.Asian journal of pharmaceutical sciences · 2020
    Review
  15. Article
  16. Article
  17. Assembly of 1Chemical science · 2019
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guocan YuState Key Laboratory of Chemical Engineering , Center for Chemistry of High-Performance & Novel Materials , Department of Chemistry , Zhejiang University , Hangzhou 310027 , P. R. China . Email: fhuang@zju.edu.cn ; ; Tel: +86-571-8795-3189.
Dan WuDepartment of Chemistry , Institute of Chemical Biology and Pharmaceutical Chemistry , Zhejiang University , Hangzhou 310027 , P. R. China.
Yang LiDepartment of Chemistry , Institute of Chemical Biology and Pharmaceutical Chemistry , Zhejiang University , Hangzhou 310027 , P. R. China.
Zhihua ZhangState Key Laboratory of Chemical Engineering , Center for Chemistry of High-Performance & Novel Materials , Department of Chemistry , Zhejiang University , Hangzhou 310027 , P. R. China . Email: fhuang@zju.edu.cn ; ; Tel: +86-571-8795-3189.
Li ShaoState Key Laboratory of Chemical Engineering , Center for Chemistry of High-Performance & Novel Materials , Department of Chemistry , Zhejiang University , Hangzhou 310027 , P. R. China . Email: fhuang@zju.edu.cn ; ; Tel: +86-571-8795-3189.
Jiong ZhouState Key Laboratory of Chemical Engineering , Center for Chemistry of High-Performance & Novel Materials , Department of Chemistry , Zhejiang University , Hangzhou 310027 , P. R. China . Email: fhuang@zju.edu.cn ; ; Tel: +86-571-8795-3189.
Qinglian HuCollege of Biological and Environmental Engineering , Zhejiang University of Technology , Hangzhou 310014 , P. R. China.
Guping TangDepartment of Chemistry , Institute of Chemical Biology and Pharmaceutical Chemistry , Zhejiang University , Hangzhou 310027 , P. R. China.
Feihe HuangState Key Laboratory of Chemical Engineering , Center for Chemistry of High-Performance & Novel Materials , Department of Chemistry , Zhejiang University , Hangzhou 310027 , P. R. China . Email: fhuang@zju.edu.cn ; ; Tel: +86-571-8795-3189.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subcellular organelle-specific reagents for simultaneous targeting, imaging and treatment are highly desirable for cancer therapy. However, it remains a challenge to fabricate a single molecular platform containing a targeting group, imaging and therapeutic agents through traditional synthesis. Due to their superior sensitivity and photostability, fluorescent probes with aggregation-induced emission (AIE) characteristics have attracted more and more attention in studying the process of translocation, drug release, and excretion of nanomedicines

Identifiers

PMID29997791
PMCPMC6003608

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.