Evidence map›Paper›PMID 29997756›Full record

ArticleElectronic physician2018

Comparison the Effectiveness of Breastfeeding, Oral 25% Dextrose, Kangaroo-Mother Care Method, and EMLA Cream on Pain Score Level Following Heal Pick Sampling in Newborns: a randomized clinical trial.

Soroosh Soltani, Dariush Zohoori, Mojtaba Adineh

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Electronic physician, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04560374 (The Effect of Using Crochet Octopus in Reducing The Pain Developed During The Process of Heel Lance İn Neonates), which is not on this map. Cited by 8 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 4 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04560374 nacompletednot on this mapstarted 2020, after this paper: background citation

The Effect of Using Crochet Octopus in Reducing The Pain Developed During The Process of Heel Lance İn Neonates: A Randomized Controlled Study

TypeinterventionalSponsorMarmara UniversityRan2020 to 2020Enrolled100ConditionsProcedural PainArmscrochet octopus
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Breastfeeding or breast milk for procedural pain in neonates.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Soroosh SoltaniMedical Student, Student Research Committee, International Branch, Shiraz University of Medical Sciences, Shiraz, Iran.
Dariush ZohooriM.D., Pediatrician, Assistant Professor, Department of Pediatrics and Neonatology, International Branch, Shiraz University of Medical Sciences, Shiraz, Iran.
Mojtaba AdinehM.D., Fellowship of Neonatalogy, Department of Pediatrics and Neonatology, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IRShiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundToday, it is considered that infants can feel pain, and it can have several adverse effects on their development. Although different interventions, such as skin-to-skin contact (kangaroo mother care method), glucose solutions, breastfeeding, and local anesthetic agents, have been evaluated to reduce infants' pain, there is no clinical trial available to identify the best method.

objectiveThe aim of this study was to compare the efficacy of four methods of relieving infants' pain, i.e., breastfeeding, oral 25% dextrose, kangaroo mother care method (KMCM), and EMLA cream based on a pain score level following heal-prick sampling in term newborns.

methodsIn this double-blind, controlled, randomized clinical trial, full term, and healthy infants in Shahid Motahhari Hospital, Marvdasht, Shiraz Province, Iran were studied. Infants were randomly allocated to four groups of interventions, i.e., A: breast milk feeding (n=42), B: oral 25% dextrose (n=40), C: KMCM (n=38), and D: KMCM ointment (n=40). All interventions were applied 15 minutes before heel-prick sampling. To evaluate the pain level in infants, the Neonatal Infant Pain Scale (NIPS) questionnaire was used. The data were analyzed with SPSS version 16 by ANOVA and the chi-squared tests.

resultsOne hundred and sixty-one infants (93 males, 68 females) with an age range of 3 to 5 days were studied. There was no significant difference between the groups in terms of gender (p=0.113), weight (p=0.059), and baseline pain score level (p=0.904). The breastfeeding method showed the lowest pain score in comparison to the other interventions (A=5.52±2.22, B=6.45±1.88, C=6.84±1.96, D=7.37±1.95; p=0.001) after the heel-prick sampling.

conclusionIt seems that, among the four methods of interventions in this study, the most effective method of lowering perceived pain in infants undergoing painful procedures was proven to be breastfeeding.

trial registrationThis study is registered in the Iranian Registry of Clinical Trials with the registration number of IRCT20151201253256N1.

fundingThis research was supported financially by the Research Council of the International Campus of Shiraz University of Medical Sciences.

Indexed as

BreastfeedingDextroseEMLAInfantKangaroo-Mother Care MethodsNeonatal Infant Pain ScalePainPain Management

Identifiers

PMID29997756
PMCPMC6033133
OpenAlexW2806073197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.