Evidence map›Paper›PMID 29997618›Full record

ReviewFrontiers in immunology2018

Immune Cell Dynamics Unfolded by Single-Cell Technologies.

Daniel J Kunz, Tomás Gomes, Kylie R James

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Epigenetic gene regulation in plasma cells.Immunological reviews · 2021
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. CD8Nature reviews. Cancer · 2020
    Review
  15. Article
  16. Article
  17. Pinpointing Cell Identity in Time and Space.Frontiers in molecular biosciences · 2020
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel J KunzCavendish Laboratory, Department of Physics, University of Cambridge, Cambridge, United Kingdom.
Tomás GomesWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Kylie R JamesWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.

Funding

Wellcome Trust
6 · The paper itself

Abstract

The single-cell revolution is paving the way towards the molecular characterisation of every cell type in the human body, revealing relationships between cell types and states at high resolution. Changes in cellular phenotypes are particularly prevalent in the immune system and can be observed in its continuous remodelling up to adulthood, response to disease and development of immunological memory. In this review, we delve into the world of cellular dynamics of the immune system. We discuss current single-cell experimental and computational approaches in this area, giving insights into plasticity and commitment of cell fates. Finally, we provide an outlook on upcoming technological developments and predict how these will improve our understanding of the immune system.

Indexed as

cell differentiationcell fateFACSlineage reconstructionmulti-omicsscRNA-seqsingle-celltrajectory inference

Identifiers

PMID29997618
PMCPMC6028612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.