Evidence map›Paper›PMID 29997588›Full record

ArticleFrontiers in microbiology2018

Functional Characterization of Enzymatic Steps Involved in Pyruvylation of Bacterial Secondary Cell Wall Polymer Fragments.

Fiona F Hager, Arturo López-Guzmán, Simon Krauter, Markus Blaukopf, Mathias Polter, Inka Brockhausen, Paul Kosma, Christina Schäffer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Identification of a second glycoform of the clinically prevalent O1 antigen fromProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Article
  5. AssayingBiomolecules · 2021
    Article
  6. Article
  7. Article
  8. Review
  9. Pyruvate Substitutions on Glycoconjugates.International journal of molecular sciences · 2019
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Fiona F HagerNanoGlycobiology Unit, Department of NanoBiotechnology, Universität für Bodenkultur Wien, Vienna, Austria.
Arturo López-GuzmánNanoGlycobiology Unit, Department of NanoBiotechnology, Universität für Bodenkultur Wien, Vienna, Austria.
Simon KrauterDivision of Organic Chemistry, Department of Chemistry, Universität für Bodenkultur Wien, Vienna, Austria.
Markus BlaukopfDivision of Organic Chemistry, Department of Chemistry, Universität für Bodenkultur Wien, Vienna, Austria.
Mathias PolterNanoGlycobiology Unit, Department of NanoBiotechnology, Universität für Bodenkultur Wien, Vienna, Austria.
Inka BrockhausenDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Paul KosmaDivision of Organic Chemistry, Department of Chemistry, Universität für Bodenkultur Wien, Vienna, Austria.
Christina SchäfferNanoGlycobiology Unit, Department of NanoBiotechnology, Universität für Bodenkultur Wien, Vienna, Austria.
BOKU University · ATQueen's University · CA

Funding

Austrian Science Fund FWF P 27374Austrian Science Fund FWF W 1224
6 · The paper itself

Abstract

Various mechanisms of protein cell surface display have evolved during bacterial evolution. Several Gram-positive bacteria employ S-layer homology (SLH) domain-mediated sorting of cell-surface proteins and concomitantly engage a pyruvylated secondary cell-wall polymer as a cell-wall ligand. Specifically, pyruvate ketal linked to β-D-ManNAc is regarded as an indispensable epitope in this cell-surface display mechanism. That secondary cell wall polymer (SCWP) pyruvylation and SLH domain-containing proteins are functionally coupled is supported by the presence of an ortholog of the predicted pyruvyltransferase CsaB in bacterial genomes, such as those of

Indexed as

glycosyltransferasemulti-enzyme assaypyruvyltransferasesecondary cell wall polymerSLH domain

Identifiers

PMID29997588
PMCPMC6030368
OpenAlexW2807255721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.