Evidence map›Paper›PMID 29997569›Full record

ArticleFrontiers in neurology2018

Reframing the Biological Basis of Neuroprotection Using Functional Genomics: Differentially Weighted, Time-Dependent Multifactor Pathogenesis of Human Ischemic Brain Damage.

William A Kofke, Yue Ren, John G Augoustides, Hongzhe Li, Katherine Nathanson, Robert Siman, Qing Cheng Meng, Weiming Bu, Sukanya Yandrawatthana, Guy Kositratna and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Identifying TBI Physiological States by Clustering Multivariate Clinical Time-Series Data.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2023
    Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

William A KofkeDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States.
Yue RenDepartment of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, United States.
John G AugoustidesDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States.
Hongzhe LiDepartment of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, United States.
Katherine NathansonDepartment of Medicine, Division of Translational Medicine and Human Genetics Abramson Cancer Center Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.
Robert SimanDepartment of Neurosurgery, University of Pennsylvania, Philadelphia, PA, United States.
Qing Cheng MengDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States.
Weiming BuDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States.
Sukanya YandrawatthanaDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States.
Guy KositratnaDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States.
Cecilia KimThe Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Joseph E BavariaDepartment of Surgery, University of Pennsylvania, Philadelphia, PA, United States.
University of Pennsylvania · USChildren's Hospital of Philadelphia · US

Funding

Genes in Human Brain IschemiaR21NS061074 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI KOFKE, W ANDREW · 2010 to 2011
$435k
NINDS NIH HHS R21 NS061074
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkerscardiac surgerycardiopulmonary bypasscerebral ischemiaclinical trialsfunctional genomicsneuroprotectionsystems biology

Identifiers

PMID29997569
PMCPMC6028620
OpenAlexW2807899726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.