Evidence map›Paper›PMID 29997245›Full record

SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2018

Systematic review of drug effects in humans and models with surfactant-processing disease.

Dymph Klay, Thijs W Hoffman, Ankie M Harmsze, Jan C Grutters, Coline H M van Moorsel

Open access · diamondAbstract readSystematic Review
In one paragraph

Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Lung-tropic dual AAV-SP-C and microRNA gene therapy attenuates lung injury in mutant Sftpc mice.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  3. Article
  4. Rare genetic interstitial lung diseases: a pictorial essay.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  5. Article
  6. ABCA3 Deficiency-Variant-Specific Response to Hydroxychloroquine.International journal of molecular sciences · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Genetic disorders of the surfactant system: focus on adult disease.European respiratory review : an official journal of the European Respiratory Society · 2021
    Article
  11. Article
  12. Functional Genomics ofAmerican journal of respiratory cell and molecular biology · 2020
    Article
  13. Review
  14. Pulmonary Fibrosis in Children.Journal of clinical medicine · 2019
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dymph KlayInterstitial Lung Disease Center of Excellence, Dept of Pulmonology, St Antonius Hospital, Nieuwegein, The Netherlands.
Thijs W HoffmanInterstitial Lung Disease Center of Excellence, Dept of Pulmonology, St Antonius Hospital, Nieuwegein, The Netherlands.
Ankie M HarmszeDept of Clinical Pharmacy, St Antonius Hospital, Nieuwegein, The Netherlands.
Jan C GruttersInterstitial Lung Disease Center of Excellence, Dept of Pulmonology, St Antonius Hospital, Nieuwegein, The Netherlands.
Coline H M van MoorselInterstitial Lung Disease Center of Excellence, Dept of Pulmonology, St Antonius Hospital, Nieuwegein, The Netherlands c.van.moorsel@antoniusziekenhuis.nl.
St. Antonius Ziekenhuis · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibrotic interstitial pneumonias are a group of rare diseases characterised by distortion of lung interstitium. Patients with mutations in surfactant-processing genes, such as surfactant protein C (

Indexed as

AnimalsDisease Models, AnimalGenetic Predisposition to DiseaseHumansIdiopathic Interstitial PneumoniasLungMiceMutationPhenotypePulmonary Surfactant-Associated ProteinsRespiratory System AgentsTreatment OutcomePulmonary Surfactant-Associated ProteinsRespiratory System Agents

Identifiers

PMID29997245
PMCPMC9489115
OpenAlexW2855545751

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.